LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

The lncRNA-MALAT1/miR-330-3p Axis Promotes Growth and Metastasis of Gastric Cancer Through Regulation of Vascular Endothelial Growth Factor A: A Genetic and Cell Evaluation Study

Hu, Zhi-li; Hu, Yang-zhi; Pan, Guang-dong.

Int. j. morphol; 42 (2), 2024

SUMMARY: Overexpression of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in various tumor tissues and cell lines was found to promote tumor cell proliferation, migration, and invasion. However, the role of MALAT1 in gastric cancer (GC) is still unclear. We aimed to investigate the corre...

Neoplasias Gástricas/patología, ARN Largo no Codificante, Proliferación Celular, Factor A de Crecimiento Endotelial Vascular, Serina-Treonina Quinasas TOR, Transducción de Señal, Neoplasias Gástricas/genética, ARN/genética, Western Blotting, Genes Reporteros, Invasividad Neoplásica, Reacción en Cadena en Tiempo Real de la Polimerasa, Regulación Neoplásica de la Expresión Génica, Movimiento Celular, Apoptosis

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Cloning of the Coffea canephora SERK1 promoter and its molecular analysis during the cell-to-embryo transition

Jiménez-Guillen, Doribet; Pérez-Pascual, Daniel; Souza-Perera, Ramón; Godoy-Hernández, Gregorio; Zúñiga-Aguilar, José Juan.

Electron. j. biotechnol; 36 (), 2018

Background: Somatic embryogenesis receptor-like kinase 1 (SERK1) is a cell membrane receptor active in different plant tissues and involved in cell differentiation activities including somatic embryogenesis. The identification of promoter elements responsible for SERK1 expression during the onset of soma...

Coffea/genética, Expresión Génica, Desarrollo Embrionario, Proteínas de Plantas/genética, Proteínas Quinasas/genética, Regulación de la Expresión Génica de las Plantas, Regiones Promotoras Genéticas, Plantas Modificadas Genéticamente, Clonación Molecular, Biotecnología, Genes Reporteros

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Improvement of clavulanic acid production in Streptomyces clavuligerus F613-1 by using a claR-neo reporter strategy

Qin, Ronghuo; Zhong, Chuanqing; Zong, Gongli; Fu, Jiafang; Pang, Xiuhua; Cao, Guangxiang.

Electron. j. biotechnol; 28 (), 2017

Background: Streptomyces clavuligerus was the producer of clavulanic acid, claR, a pathway-specific transcriptional regulator in S. clavuligerus, positively regulates clavulanic acid biosynthesis. In this study, the promoter-less kanamycin resistance gene neo was fused with claR to obtain strain NEO from...

Streptomyces/metabolismo, Ácido Clavulánico/biosíntesis, Mutagénesis, Fermentación, Genes Reporteros, Regiones Promotoras Genéticas, Transcripción Genética, Streptomyces/genética, Bioensayo, Cromatografía Líquida de Alta Presión, Reacción en Cadena en Tiempo Real de la Polimerasa, Fusión Génica, Kanamicina, Proteínas Recombinantes, Factores de Transcripción/genética

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