Are statins a risk factor in patients with atherosclerosis?
Int. j. morphol; 40 (5), 2022
SUMMARY: Statins inhibit cholesterol synthesis, but also have other pleiotropic effects. There are indications that they affect macrophage survival trough the regulation of apoptosis. We analyzed 50 samples of aortic wall, selected based on statins in patients' therapy (n=25, Th-S group) or statin-free t...
Inhibidores de Hidroximetilglutaril-CoA Reductasas/administración & dosificación, Aterosclerosis/metabolismo, Apoptosis/efectos de los fármacos, Proteína bcl-X/metabolismo, Genes bcl-2/fisiología, Macrófagos/efectos de los fármacos, Aorta/efectos de los fármacos, Aterosclerosis/tratamiento farmacológico, Placa Aterosclerótica, Factores de Riesgo, Medición de Riesgo