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The search for novel insecticide targets in the post-genomics era, with a specific focus on G-protein coupled receptors

Ngai, Michelle; McDowell, Mary Ann.
Mem. Inst. Oswaldo Cruz; 112 (1), 2017
Insects are considered pests globally, implicated in the destruction of agricultural fields and transmission of pathogens that cause deadly human diseases, such as dengue, Zika and malaria. The diversity of the insecticide arsenal has remained stagnant for decades, but the recent rise of insecticide resi...
Marcación de Gen/métodos, Genoma de los Insectos, Control de Insectos/métodos, Resistencia a los Insecticidas, Insecticidas, Interferencia de ARN, Receptores Acoplados a Proteínas G/genética, Receptores Acoplados a Proteínas G/metabolismo
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A possible role of Drosophila CTCF in mitotic bookmarking and maintaining chromatin domains during the cell cycle

Shen, Wenlong; Wang, Dong; Ye, Bingyu; Shi, Minglei; Zhang, Yan; Zhao, Zhihu.
Biol. Res; 48 (), 2015
BACKGROUND: The CCCTC-binding factor (CTCF) is a highly conserved insulator protein that plays various roles in many cellular processes. CTCF is one of the main architecture proteins in higher eukaryotes, and in combination with other architecture proteins and regulators, also shapes the three-dimensiona...
Cromatina/fisiología, Proteínas de Drosophila/fisiología, Drosophila melanogaster/química, Genoma de los Insectos/genética, Mitosis/fisiología, Proteínas Represoras/fisiología, Ciclo Celular/fisiología, Ensamble y Desensamble de Cromatina/fisiología, Interfase/fisiología, Secuencia de Bases, Sitios de Unión, Factor de Unión a CCCTC, Biología Computacional, Secuencia Conservada, Conjuntos de Datos como Asunto, Anotación de Secuencia Molecular, Sintenía
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