ABSTRACT Objective To evaluate the influence of self-reported sleep duration on ghrelin secretion and nutritional indicators in obese women. Methods This is an observational study, including 36 adult women with obesity. Sleep duration was reported while completing the general questionnaire. Dietary, la...
BACKGROUND: Appetite regulation is integral to food intake and is modulated by complex interactions between internal and external stimuli. Hormonal mechanisms which stimulate or inhibit intake have been characterized, but the physiologic effects of serum levels of such hormones in short-term appetite reg...
SUMMARY: This study aimed to investigate the effect of exogenous ghrelin on pancreatic growth and development in African ostrich chicks. Sixteen 40-day-old African ostrich chicks (male or female) were randomly divided into four groups and injected intravenously metatarsal vein with saline (control) or gh...
Asadi, Asadollah;
Farahani, Hamid;
Mahmoudi, Touraj;
Tabaeian, Seidamir Pasha;
Rezamand, Gholamreza;
Mohammadbeigi, Abolfazl;
Dabiri, Reza;
Nobakht, Hossein;
Rezvan, Sajad;
Mohammadi, Fatemeh.
ABSTRACT BACKGROUND AND OBJECTIVE: Considering the association between colorectal cancer (CRC) and both insulin resistance and obesity, and the prominent role of ghrelin in these metabolic disorders, we explored whether plasma levels of ghrelin were associated with CRC. Moreover, in the patients with C...
SUMMARY OBJECTIVE: Epilepsy is a common disorder that affects the nervous systems of 1% of worldwide population. In epilepsy, one-third of patients are unresponsive to current drug therapies and develop drug-resistant epilepsy. Alterations in ghrelin, nesfatin-1, and irisin levels with epilepsy were rep...
ABSTRACT Objective: This study investigated the acute effects of high-intensity interval (HIIE) and moderate-intensity continuous (MICE) exercise on ghrelin levels in obese men. Subjects and methods: A total of 10 obese men (age 27.6 ± 1.8 years, body mass index 35.4 ± 4.5 kg/m², body fat 39.9 ± 2....
Resumen Objetivo: La cirugía bariátrica es un procedimiento para disminuir de peso a largo plazo en pacientes con obesidad. El objetivo de este estudio fue evaluar los niveles de ghrelina y la reducción del peso de acuerdo al tipo de cirugía bariátrica, comparando el bypass de una sola anastomosis y...
SUMMARY OBJECTIVE We aimed to explore the effects of neuropeptides ghrelin, obestatin, and vasoactive intestinal peptide (VIP) on seizures and plasma concentrations of neuroinflammation biomarkers including calcitonin gene-related peptide (CGRP), substance-P (SP), and interleukin-1 beta (IL-1β) in...
Biomarcadores/sangre,
Péptido Relacionado con Gen de Calcitonina/sangre,
Péptido Relacionado con Gen de Calcitonina/efectos adversos,
Convulsivantes/efectos adversos,
Modelos Animales de Enfermedad,
Ghrelina/farmacología,
Inflamación,
Interleucina-1beta/sangre,
Interleucina-1beta/efectos adversos,
Mioclonía,
Neuropéptidos/efectos adversos,
Pentilenotetrazol/efectos adversos,
Hormonas Peptídicas/farmacología,
Distribución Aleatoria,
Ratas Wistar,
Convulsiones/inducido químicamente,
Convulsiones/metabolismo,
Sustancia P/sangre,
Sustancia P/efectos adversos,
Factores de Tiempo,
Péptido Intestinal Vasoactivo/farmacología
Ghrelin is a novel growth hormone-releasing peptide administered to treat myocardial infarction (MI). However, the underlying mechanism of its protective effects against MI remains unclear. A total of sixty healthy Sprague Dawley male rats were included. The first one is the sham-operated control group w...
