LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Differential immunohistochemical expression of type I collagen and matrix metalloproteinase 2 among major salivary glands of young and geriatric mice

Tumer, Mehmet Kemal; Cicek, Mustafa.

J. appl. oral sci; 26 (), 2018

Abstract Objective This study aimed to demonstrate the immunohistochemical changes associated with MMP-2 and type 1 collagen separately for the first time in the major salivary glands (the parotid, submaxillary, and sublingual glands) that occur with aging in mice. Material and Methods Fourteen Balb/...

Factores de Edad, Colágeno Tipo I/análisis, Inmunohistoquímica, Metaloproteinasa 2 de la Matriz/análisis, Ratones Endogámicos BALB C, Glándula Parótida/química, Glándula Parótida/patología, Glándula Parótida/fisiopatología, Valores de Referencia, Glándula Sublingual/química, Glándula Sublingual/patología, Glándula Sublingual/fisiopatología, Glándula Submandibular/química, Glándula Submandibular/patología, Glándula Submandibular/fisiopatología

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Immunolocalization of the TGFB1 system in submandibular gland fibrosis after experimental periodontitis in rats

Saliva is the first barrier to entry of bacteria and viruses into the body. The submandibular glands (SMG) contribute to the maintenance of oral health and regulation of immune/ inflam matory responses. Previous studies suggest that transforming growth factor beta 1 (TGFB1) may contribute to salivary gla...