Results: 5

Antígeno del factor von Willebrand (FVW: Ag)

Med. lab; 27 (2), 2023
Utilidad clínica de la prueba El factor von Willebrand (FVW) es una glicoproteína compuesta por multímeros con pesos moleculares que pueden variar desde 500 KDa hasta 20.000 kDa, que se sintetiza en las células endoteliales y en los megacariocitos, y se almacena en los cuerpos de Weibel-Palade y en l...

Índice de Salud Prostática (phi)

Med. lab; 26 (1), 2022
El antígeno específico de próstata (PSA, del inglés, Prostate Specific Antigen) es una glicoproteína producida por la próstata, y es el marcador tumoral de mayor uso. Sin embargo, su baja especificidad para diferenciar entre cáncer de próstata y otras alteraciones no malignas, como la hipertrofia...

Platelet activating factor receptor antagonists improve the efficacy of experimental chemo- and radiotherapy

Clinics; 73 (supl.1), 2018
Platelet activating factor is a lipid mediator of inflammation, and in recent decades, it has emerged as an important factor in tumor outcomes. Platelet activating factor acts by specific binding to its receptor, which is present in both tumor cells and cells that infiltrate tumors. Pro-tumorigenic effec...

Gene mutations of platelet glycoproteins and response to tirofiban in acute coronary syndrome

Säo Paulo med. j; 134 (3), 2016
CONTEXT AND OBJECTIVES: Glycoprotein inhibitors (abciximab, eptifibatide and tirofiban) are used in patients with unstable angina and non-ST-segment elevation myocardial infarction before percutaneous coronary intervention. Of these, tirofiban is the least effective. We hypothesized that the response to...

Impacto de los polimorfismos de las glucoproteínas plaquetarias sobre la enfermedad coronaria

Myocardial infarction is usually the consequence of intravascular thrombus formation superimposed upon ruptured plaque in a coronary artery. Platelets plays a pivotal role in the initiation and thrombus formation. A lot of conflicting studies have evaluated the relations between various platelet glycopro...