LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Clinical and histological features of patients with membranoproliferative glomerulonephritis classified by immunofluorescence findings

Abstract Background: New classification for membranoproliferative glomerulonephritis has been proposed in the literature. The aim of this study was to compare the clinical, biochemical, etiology and renal biopsy findings of these patients grouped by immunofluorescence as proposed by the new classificati...

Shenhua Tablet inhibits mesangial cell proliferation in rats with chronic anti-Thy-1 nephritis

Geng, Wenjia; Wei, Ribao; Liu, Shuwen; Tang, Li; Zhu, Hanyu; Chen, Pu; Wu, Jie; Zhang, Xueguang; Zhu, Fei; Yin, Zhong; Chen, Xiangmei.

Biol. Res; 49 (), 2016

BACKGROUND: In China, mesangial proliferative glomerulonephritis (MsPGN) is one of the most common kidney diseases. In this study, we treated a rat model of chronic anti-Thy-1 MsPGN with Shenhua Tablet and evaluated whether the tablet was able to protect the kidney function. Thirty-six Wistar rats were r...

Proliferación Celular/efectos de los fármacos, Medicamentos Herbarios Chinos/farmacología, Glomerulonefritis Membranoproliferativa/tratamiento farmacológico, Células Mesangiales/efectos de los fármacos, Isoanticuerpos, Ciclina D1/análisis, Medicamentos Herbarios Chinos/uso terapéutico, Glomerulonefritis Membranoproliferativa/patología, Proteína Quinasa 1 Activada por Mitógenos/análisis, Albúmina Sérica/análisis, Quinasas p21 Activadas/análisis, Enfermedad Crónica, Ratas Wistar, Reproducibilidad de los Resultados, Computadoras de Mano, Factores de Tiempo

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