Results: 42

Evaluation of effect of Nerium oleander against STZ induced diabetic neuropathy rat model by reducing NF-κB pathway

Diabetic neuropathy (DN) is a chronic diabetic complication, which is difficult to manage. The current investigation evaluates the effect of Nerium oleander (NO) in the management of diabetic neuropathy (DN). Diabetic neuropathy was induced by streptozotocin (STZ) [60 mg/kg, i.p.] and treated ...

Efectos de los edulcorantes no nutritivos sucralosa y estevia en personas con diabetes tipo 1 y 2

INTRODUCCIÓN: El aumento global de la prevalencia de la diabetes ha generado un interés creciente en terapias alternativas, incluyendo el uso de edulcorantes no nutritivos (ENN) en reemplazo de la sacarosa. En el mercado chileno la sucralosa y la estevia son los más utilizados. OBJETIVO: Describir los...

Effects of an antioxidants cocktail on glucose metabolism at rest, during exercise, and during a glucose load in healthy young subjects

Rev. chil. nutr; 50 (6), 2023
Background: Reactive oxygen species (ROS) regulate glucose metabolism (GM) in skeletal muscle by improving the translocation of GLUT4. Antioxidant supplementation could block this physiological effect, altering glucose signaling during exercise. However, there is limited evidence in humans on whether ant...

Anti-hyperglycemic activity of aqueous extracts of cells produced in Ibervillea sonorae (S. Watson) Green cell culture on murine model

Ibervillea sonorae (S. Watson) Greene, is a plant native to Mexico, where its roots have been used traditionally for treating Diabetes Mellitus. The aim of this work was to establishment of cell cultures of stem explants of I. sonorae and evaluation of the anti-hyperglycemic activity of ...

Evaluación de una nueva formulación de compuestos naturales sobre la modificación de los componentes del síndrome metabólico en adultos con sobrepeso

Rev. chil. nutr; 49 (6), 2022
El sobrepeso y la obesidad, condiciones cada vez más frecuentes en Chile y el Mundo, se definen como una enfermedad crónica caracterizada por la acumulación excesiva de grasa corporal que puede ser perjudicial para la salud. El exceso de grasa corporal es el principal factor patogénico para el desarr...

Cyperus esculentus L. protects testis and sperm morphology of hyperglycaemic rats

Cyperus esculentus L. (tiger nut) is a tuberous plant that promotes and protects reproductive functions, which are usually hampered in diabetics. The present study investigated the effect of Cyperus esculentus tuber extract (CETE) on testicular histology and sperm viability of all...

Análisis comparativo de respuesta glicémica y de péptido C, tras la ingesta de estevia y D-tagatosa, según habitualidad de consumo de edulcorantes no nutritivos y preferencias alimentarias reportadas por mujeres con resistencia a la insulina

INTRODUCCIÓN: El consumo de edulcorantes no nutritivos (ENN) ha ido en aumento. A pesar de ello, se desconoce el efecto entre el consumo habitual de ENN y las preferencias alimentarias con parámetros bioquímicos en pacientes con resistencia a la insulina. OBJETIVO: Comparar la respuesta glicémica y d...

Hypolipidemic, hipoglycemiant and antioxidant effects of Myrcia splendens (Sw) DC in an animal type 2 diabetes model induced by streptozotocin

We investigated the effects of dichloromethane extract (DME) from Myrcia splendenson alterations caused by type 2 diabetes in the blood and kidney of rats, in order to reduce side effects caused by synthetic drugs. Rats received streptozotocin (60 mg/kg),15 minutes after nicotinamide (120 mg/kg) or water...

Pharmacological evaluation of Rhazya stricta root extract

The present study aimed to screen the Rhazya stricta Decne root for its antihyperglycemic and antioxidants potential through invitro assays along with phytochemical and elemental analyses. The crude extract was prepared through maceration and fractionated using solvent-solvent extraction technique. The s...

Effect of low-fat diets enriched with fruit purees on the biochemical markers of metabolic syndrome analogy induced-rats

Int. j. morphol; 38 (1), 2020
Fruit purees can be added to diet as alternative sources of bioactive compounds for the prevention and/or improvement of the complications of metabolic syndrome. In this work we evaluated the effect of the intake of low-fat diets enriched with fruit purees (guava-strawberry, guava-blackberry, guava-sours...