Results: 3

Validation of the rapid test carestart(tm) G6PD among malaria vivax-infected subjects in the Brazilian Amazon

Abstract: INTRODUCTION: In the Brazilian Amazon, malaria infections are primarily caused by Plasmodium vivax. The only drug that kills the hypnozoite form of P. vivax is primaquine, thereby preventing relapse. However, treating glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals with primaqui...

Erythrocyte oxidative stress markers in children with sickle cell disease

J. pediatr. (Rio J.); 92 (4), 2016
Abstract Objective To determine eight parameters of oxidative stress markers in erythrocytes from children with sickle cell disease and compare with the same parameters in erythrocytes from healthy children, since oxidative stress plays an important role in the pathophysiology of sickle cell disease and...

Glicose-6-fosfato desidrogenase e 6-fosfogliconato desidrogenase: atividade e cinética em condiçöes fisiológicas

Foram determinadas as atividades enzimaticas da G-6-PDG aos seus substratos G-6-P e 6-PGA respectivamente, em sistemas reagentes recomendados pela OMS e em condiçöes próximas às fisiológicas intraeritrocitárias de pH, temperatura, força iônica, e concentraçäo de moduladores, de indivíduos norm...