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Evaluating Aprepitant single-dose plus granisetron and dexamethasone in children receiving highly emetogenic chemotherapy for the prevention of chemotherapy-induced nausea and vomiting: A triple-blinded randomized clinical trial

Eghbali, Aziz; Kohpar, Fatemeh Khazaei; Ghaffari, Kazem; Afzal, Roghayeh Rahimi; Eghbali, Aygin; Ghasemi, Ali.
Hematol., Transfus. Cell Ther. (Impr.); 45 (3), 2023
ABSTRACT Introduction: This study was performed to evaluate the degree of 3-day chemotherapy-induced nausea and vomiting (CINV) in children with cancer who received highly emetogenic chemotherapy (HEC) to ascertain the efficacy of aprepitant single-dose on dayL 1 plus granisetron and dexamethasone (DEX)...
Aprepitant, Náusea, Vómitos, Dexametasona, Granisetrón
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Comparison of granisetron and lidocaine on reducing injection pain of etomidate: a controlled randomized study

Saliminia, Alireza; Azimaraghi, Omid; Javadi, Amir; Abdoulahpoor, Maryam; Movafegh, Ali.
Rev. bras. anestesiol; 67 (6), 2017
Abstract Background and objectives Reducing pain on injection of anesthetic drugs is of importance to every anesthesiologist. In this study we pursued to define if pretreatment by granisetron reduces the pain on injection of etomidate similar to lidocaine. Methods Thirty patients aged between 18 and 50...
Anestésicos Intravenosos/efectos adversos, Método Doble Ciego, Etomidato/efectos adversos, Granisetrón/uso terapéutico, Inyecciones Intravenosas, Lidocaína/uso terapéutico, Persona de Mediana Edad, Dolor/inducido químicamente, Dolor/tratamiento farmacológico, Manejo del Dolor/métodos
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Formulation and evaluation of taste mask pellets of granisetron hydrochloride as oro dispersible tablet

Choudhary, Nilesh; Avari, Jasmine.
Braz. j. pharm. sci; 51 (3), 2015
Orally disintegrating systems have carved a niche amongst the oral drug delivery systems due to the highest compliance of the patients, especially the geriatrics and pediatrics. In addition, patients suffering from dysphagia, motion sickness, repeated emesis and mental disorders prefer these medications ...
Granisetrón/análisis, Comprimidos/farmacocinética, Vías de Administración de Medicamentos, Administración Bucal, Química Farmacéutica
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