Ullah, N;
Kakakhel, M A;
Bai, Y;
Xi, L;
Khan, I;
Kalra, B S;
Kumar, T;
Ahmad, H;
Shah, M;
Guanlan, L;
Zhang, C.
Abstract Hepatitis C virus (HCV) is the serious global public health burden of liver disease. Approximately 170 million people in the world are infected with (HCV). In Pakistan, where the disease has high occurrence rate. The present study envisages an up-to-date prevalence of HCV and genotypic distribut...
ABSTRACT OBJECTIVE To determine the seroprevalence of hepatitis B and C among immigrants residing refugee camps in Muzaffarabad, Azad Kashmir, Pakistan, and to identify possible risk factors for hepatitis B virus (HBV) and hepatitis C virus (HCV) transmission. METHODS Around 1,225 individuals inhabit...
Brasil,
Hepacivirus/genética,
Antígenos de Superficie de la Hepatitis B,
Virus de la Hepatitis B/genética,
Hepatitis B/epidemiología,
Anticuerpos contra la Hepatitis C,
Hepatitis C/diagnóstico,
Hepatitis C/epidemiología,
Pakistán/epidemiología,
Refugiados,
Estudios Seroepidemiológicos
SUMMARY OBJECTIVE: This study aimed to compare the serum samples found reactive (≥1-≤20 signal-to-cutoff ratio) with Elecsys antibodies to hepatitis C virus screening test with innogenetics-line immunassay hepatitis C Virus Score test and to determine the most appropriate threshold value for...
INTRODUCCIÓN: La medición de carga viral (CV) de virus hepatitis B (VHB) y C (VHC) es fundamental en el seguimiento de pacientes con terapia antiviral. La metodología más utilizada para su determinación es COBAS ®-TaqMan ®. Recientemente, se desarrolló la tecnología Xpert ®, que se debe evaluar...
Zitelli, Patricia Momoyo Yoshimura;
Gomes-Gouvêa, Michele;
Mazo, Daniel F.;
Singer, Julio da Motta;
Oliveira, Claudia P.M.S.;
Farias, Alberto Queiroz;
Pinho, João Renato;
Tanigawa, Ryan Yukimatsu;
Alves, Venâncio Avancini Ferreira;
Carrilho, Flair José;
Pessoa, Mário Guimarães.
OBJECTIVES: Co-infection with hepatitis A or B viruses may aggravate liver injury in patients infected with hepatitis C virus (HCV). However, few studies have assessed co-infection with hepatitis E virus (HEV) and HCV. Therefore, this study aimed to assess the prevalence and impact of HEV infection among...
Coinfección,
Diabetes Mellitus/epidemiología,
Hepacivirus/genética,
Anticuerpos Antihepatitis,
Hepatitis C,
Hepatitis C Crónica/complicaciones,
Virus de la Hepatitis E/genética,
Hepatitis E/complicaciones,
Hepatitis E/epidemiología,
Prevalencia,
ARN Viral
Abstract INTRODUCTION: We compared the hepatitis C virus (HCV) core antigen test with the HCV RNA assay to confirm anti-HCV results to determine whether the HCV core antigen test could be used as an alternative confirmatory test to the HCV RNA test. METHODS: Sera from 156 patients were analyzed for an...
ABSTRACT Introduction: Hepatitis C virus (HCV) infection continues to be an important public health problem worldwide. Despite the availability of drugs that promote the cure of infection in more than 95% of cases, the identification of HCV carriers remains a major challenge. Objective: To evaluate a s...
ABSTRACT A retrospective cohort of 11,308 chronic hepatitis C infected patients treated with regimens that included Sofosbuvir (SOF), Daclatasvir (DCV), Simeprevir (SMV), or an association of Ombitasvir, Veruprevir/Ritonavir and Dasabuvir (3D) with or without Ribavirin (RBV) were assessed for sustained v...
Antivirales/uso terapéutico,
Brasil,
Quimioterapia Combinada,
Genotipo,
Hepacivirus/genética,
Hepatitis C/tratamiento farmacológico,
Hepatitis C Crónica/tratamiento farmacológico,
Persona de Mediana Edad,
Estudios Retrospectivos,
Ribavirina/uso terapéutico,
Resultado del Tratamiento
ABSTRACT BACKGROUND: Chronic hepatitis C still figures as an important cause of morbidity among the Brazilian population, and is closely associated with metabolic disturbances, including insulin resistance (IR), which can be evaluated by the Homeostatic Model Assessment (HOMA-IR). IR may entail lower s...
Abstract Background Despite the emergence of more effective therapies, hepatitis C virus (HCV) infection remains a serious public health problem at the global level. Currently, this virus is classified into seven genotypes and 67 subgenotypes, which in turn are distributed heterogeneously in Brazil and ...