LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Predictors of HBeAg seroconversion after long-term nucleos(t)ide analogues treatment for chronic hepatitis B: a multicenter study in real clinical setting

Yu, Weiyan; Wang, Yadong; Shen, Chuan; Ji, Ru; Zhang, Li; Zhao, Xin; Su, Miao; Zhang, Ying; He, Wenyan; Cao, Jianguo; Hao, Yanshuang; Chen, Shengpeng; Zhao, Caiyan.

Braz. j. infect. dis; 21 (3), 2017

ABSTRACT Aims: To evaluate the HBeAg seroconversion rate in real clinical setting and explore its predictors in long-term nucleos(t)ide analogues (NAs) treatment for chronic hepatitis B (CHB). Methods: 251 patients were recruited from January 2001 to September 2009 in four hospitals in Hebei province, ...

Alanina Transaminasa/sangre, Antivirales/administración & dosificación, Estudios de Casos y Controles, Quimioterapia Combinada, Antígenos e de la Hepatitis B/sangre, Hepatitis B Crónica/tratamiento farmacológico, Hepatitis B Crónica/enzimología, Hepatitis B Crónica/inmunología, Estudios Retrospectivos, Seroconversión/efectos de los fármacos, Factores de Tiempo, Resultado del Tratamiento

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Association of PRKAA1 gene polymorphisms with chronic hepatitis B virus infection in Chinese Han population

ABSTRACT Objective: Studies have indicated that AMPK play critical roles in the regulation of innate immunity and inflammatory responses. However, the role of the polymorphisms of PRKAA1 gene in immune-response to infectious organisms remains unknown. To evaluate the potential role of PRKAA1/AMPKα1...