Linderae radix ethanol extract attenuates alcoholic liver injury via attenuating inflammation and regulating gut microbiota in rats
Braz. j. med. biol. res; 52 (6), 2019
This study aimed to explore the influence of gut microbiota alterations induced by Linderae radix ethanol extract (LREE) on alcoholic liver disease (ALD) in rats and to study the anti-inflammatory effect of LREE on ALD through the lipopolysaccharide (LPS) toll-like receptor 4 (TLR4)-nuclear factor kappa ...
Citocinas/sangre, Modelos Animales de Enfermedad, Microbioma Gastrointestinal/efectos de los fármacos, Inflamación/prevención & control, Lindera/química, Lipopolisacáridos/sangre, Hígado/ultraestructura, Hepatopatías Alcohólicas/diagnóstico por imagen, Hepatopatías Alcohólicas/prevención & control, Extractos Vegetales/farmacología, Raíces de Plantas/química, Proteínas Serina-Treonina Quinasas/sangre, Ratas Sprague-Dawley, Receptor Toll-Like 4/sangre