Floating tablets of hydralazine hydrochloride: optimization and evaluation
Braz. j. pharm. sci; 49 (4), 2013
Hydralazine hydrochloride has a half-life of 2 to 4 hours with an oral bioavailability of 26-50%. Since hydralazine has a demethylating effect on various suppressor genes, it can be used in various types of cancer to support chemotherapy. The purpose of this study was to optimize and evaluate floating ta...