INTRODUCTION: Plantar vein thrombosis is a rare condition that can lead to pain, edema, and walking difficulties. It presents a series of predisposing factors, such as recent surgeries, the use of oral contraceptives, and local trauma, among others. Imaging tests are essential for the right diagnosis, an...
Esta revisión busca proporcionar a los profesionales de la salud una mayor comprensión del dolor para su actividad clínica-asistencial. Basados en la hipóte-sis de neuroplasticidad presentada inicialmente por Ramón y Cajal y la teoría de la compuerta en la vía dolorosa presentada por Melzack ...
Vasudevan, Rajalakshimi;
Kandasamy, Geetha;
Almaghaslah, Dalia;
Almanasef, Mona;
Alqahatani, Ali;
Aldahish, Afaf;
Venkatesan, Krishnaraju;
Paulsamy, Premalatha;
Maheswari, C;
Wahab, Shadma.
Abstract Neuropathic pain is generally characterised by an abnormal sensation (dysesthesia), an increased response to painful stimuli (hyperalgesia), and pain in response to a stimulus that does not normally provoke pain (allodynia). The present study was designed to investigate the effect of trazodone (...
Abstract Diabetic Neuropathy (DN) is one of the prevailing micro vascular complications of diabetes which can be characterized by neuropathic pain. Streptozotocin (STZ) induced diabetes in the rat has been increasingly used as a model of painful diabetic neuropathy. STZ injection leads to neurotoxicity o...
Abstract Neuropathic pain (NP) affects more than 8% of the global population. The proposed action of the transient receptor potential ankyrin 1 (TRPA1) as a mechanosensor and the characterization of the transient receptor potential melastatin 8 (TRPM8) as a cold thermosensor raises the question of wheth...
ABSTRACT Purpose To explore the role and molecular mechanisms of neuroprotective effects of octreotide in alcohol-induced neuropathic pain. Methods Male Wistar rats were employed and were administered a chronic ethanol diet containing 5% v/v alcohol for 28 days. The development of neuropathic pain was ...
Analgésicos/farmacología,
Factor Neurotrófico Derivado del Encéfalo,
Cistationina betasintasa,
Etanol,
Sulfuro de Hidrógeno,
Hiperalgesia,
Factor 2 Relacionado con NF-E2,
Neuralgia/inducido químicamente,
Neuralgia/tratamiento farmacológico,
Octreótido/farmacología,
Ratas Wistar,
Factor de Necrosis Tumoral alfa,
Cistationina gamma-Liasa
Reactive oxygen species (ROS) are involved in neuropathic pain, a complicated condition after nerve tissue lesion. Vitamin D appears to improve symptoms of pain and exhibits antioxidant properties. We investigated the effects of oral administration of vitamin D3, the active form of vitamin D, on nocicept...
Antioxidantes,
Peróxido de Hidrógeno,
Hiperalgesia/tratamiento farmacológico,
Neuralgia/tratamiento farmacológico,
Nocicepción,
Ratas Wistar,
Especies Reactivas de Oxígeno,
Nervio Ciático,
Médula Espinal,
Vitamina D,
Vitaminas
OBJETIVO: analisar parâmetros clínicos sugestivos de sensibilização central em mulheres com disfunção temporomandibular dolorosa crônica antes e após uma intervenção baseada em mindfulness. MÉTODO: onze mulheres com idade entre 27 e 44 anos (36,36 ± 5,61), com diagnóstico de disfunções tem...
INTRODUCTION: Different studies have evaluated the effects of electrophysical agents on regeneration after peripheral nerve injury. Among them, the most used in clinical and experimental research is photobiomodulation therapy (PBMT). OBJECTIVE: To analyze the effect of standard energy (16.8 J) of PBMT on...
A analgesia preemptiva tem como princípio a administração de fármacos antes do início dos estímulos dolorosos, a fim de reduzir ou prevenir a dor pós-operatória. Apesar da sua importância, os efeitos da analgesia preemptiva em cirurgias odontológicas reportados na literatura ainda são conflita...
