Results: 2

Short-term perinatal oxygen exposure may impair lung development in adult mice

Kumar, Vasantha H. S; Wang, Huamei; Nielsen, Lori.

Biol. Res; 53 (), 2020

BACKGROUND: Hyperoxia at resuscitation increases oxidative stress, and even brief exposure to high oxygen concentrations during stabilization may trigger organ injury with adverse long-term outcomes in premature infants. We studied the long-term effects of short-term perinatal oxygen exposure on cell cyc...

Hiperoxia/patología, Pulmón/patología, Oxígeno/efectos adversos, Elastina/metabolismo, Pulmón/crecimiento & desarrollo, Estrés Oxidativo

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Ultrastructural morphological alterations during hyperoxia exposure in relation to glutathione peroxidase activity and free radicals productions in the mitochondria of the cortical brain

Bin-Jaliah, Ismaeel; Haffor, Al-Said.

Int. j. morphol; 36 (4), 2018

Exposure to normobaric hyperoxia (NH) is known to increase the production of reactive oxygen species (ROS) by mitochondria. The present study was designed to examine mitochondrial ultrastructure morphological changes in the cortical brainin relation to glutathione peroxidase (GPX) activity and free radic...

Hiperoxia/patología, Corteza Cerebral/patología, Corteza Cerebral/ultraestructura, Glutatión Peroxidasa/metabolismo, Especies Reactivas de Oxígeno, Especies de Nitrógeno Reactivo, Mitocondrias/patología, Corteza Cerebral/enzimología, Análisis de Varianza, Mitocondrias/ultraestructura, Ratas Wistar