Abstract: The Nevoid Basal Cell Carcinoma Syndrome (NBCCS) is an uncommon disorder caused by a mutation in Patched, tumor suppressor gene. It is mainly characterized by numerous early onset basal cell carcinomas, odontogenic cysts of jaw and skeletal abnormalities. Due to the wide clinical spectrum, trea...
The Gorlin-Goltz syndrome (GGS) is a hereditary, autosomal dominant
condition, with high penetrance and variable expressivity, resulting from
mutations in the genes PTCH1, PTCH2, or SUFU. The diagnosis is based on
the presence of 2 major criteria or a major criterion associated with 2 minor
criteria, inc...
