Abstract Background: A family history of arterial hypertension (AH), combined with environmental risk factors, is directly related to the development of AH. Objectives: To evaluate the frequency of AH, anthropometric indicators and level of physical activity and their association with a family history ...
Resumo Fundamento A história familiar de hipertensão (HFH) é um fator de risco consistente para diversas doenças crônicas que são acompanhadas por hipertensão. Além disso, a variabilidade da frequência cardíaca (VFC) e a vasodilatação mediada pelo fluxo (VMF), ambas relacionadas ao consumo ...
Abstract Background: Individuals with a family history of systemic arterial hypertension (FHSAH) and / or prehypertension have a higher risk of developing this pathology. Objective: To evaluate the autonomic and vascular functions of prehypertensive patients with FHSAH. Methods: Twenty-five young volu...
ABSTRACT Objective Obesity can cause systemic arterial hypertension (SAH) and type 2 diabetes mellitus (DM2) factor that is also influenced by genetic variability. The present study aims to investigate the association between gene polymorphisms related with obesity on the prevalence of SAH and DM2 in t...
Diabetes Mellitus Tipo 2/epidemiología,
Diabetes Mellitus Tipo 2/genética,
Derivación Gástrica,
Hipertensión/epidemiología,
Hipertensión/genética,
Obesidad/complicaciones,
Obesidad/genética,
Obesidad/cirugía,
Polimorfismo Genético,
Periodo Posoperatorio,
Periodo Preoperatorio,
Prevalencia,
Estudios Prospectivos,
Proteína Desacopladora 3/genética
La hipertensión arterial es una enfermedad común, que constituye un factor de riesgo de enfermedad cardiovascular, y causa alrededor de 13,5 millones de muertes anuales en el mundo. Más de 65 millones de personas en los Estados Unidos, y un billón en el mundo padecen de hipertensión arterial; en Cub...
Background: Renal function declines according to age and vascular risk factors, whereas few data are available regarding geneticallymediated effects of anti-hypertensives over renal function. Objective: To estimate urea and creatinine variations in dementia due to Alzheimer disease (AD) by way of a pharm...
Enfermedad de AlzheimerSangre,
Inhibidores de la Enzima Convertidora de Angiotensina/farmacología,
CreatininaSangre,
Peptidil-Dipeptidasa A/genética,
UreaSangre,
Factores de Edad,
Alelos,
Presión Sanguínea/efectos de los fármacos,
Presión Sanguínea/genética,
AyunoSangre,
Frecuencia de los Genes,
Genotipo,
Hipertensión/tratamiento farmacológico,
Hipertensión/genética
Herrera, Christian L;
Castillo, Wilma;
Estrada, Patricia;
Mancilla, Bárbara;
Reyes, Gerardo;
Saavedra, Nicolás;
Guzmán, Neftalí;
Serón, Pamela;
Lanas, Fernando;
Salazar, Luis A.
ABSTRACT Objective Metabolic syndrome (MetS) is associated with hypertension, obesity and dyslipidemia. Thus, genetic variants related with these conditions may modulate its development. We evaluated the effect of polymorphisms in the renin-angiotensin system (RAS) on metabolic syndrome risk in a cohort...
Factores de Edad,
Angiotensinógeno/genética,
Chile,
Estudios de Cohortes,
Estudios Transversales,
Eliminación de Gen,
Predisposición Genética a la Enfermedad,
Genotipo,
Hipertensión/genética,
Síndrome Metabólico/genética,
Peptidil-Dipeptidasa A/genética,
Polimorfismo Genético,
Receptor de Angiotensina Tipo 1/genética,
Sistema Renina-Angiotensina/genética,
Factores Sexuales
Wang, Zhong;
Chen, Shaoze;
Zhang, Lina;
Lu, Guilin;
Zhou, Chengming;
Wang, Dao Wen;
Wang, Li;
Badengmu, Bayinbate;
Zhai, Zhihong;
Qin, Lian.
CONTEXT AND OBJECTIVE: Dimethylarginine dimethylaminohydrolase enzymes (DDAH), which are encoded by the genes DDAH1 and DDAH2, play a fundamental role in maintaining endothelial function. We conducted a case-control study on a Chinese population that included three ethnic groups (Han, Kazakh and Uygur),...
Amidohidrolasas/genética,
Pueblo Asiatico/genética,
Secuencia de Bases,
Estudios de Casos y Controles,
China/etnología,
Etnicidad/genética,
Variación Genética,
Genotipo,
Hipertensión/epidemiología,
Hipertensión/genética,
Factores de Riesgo
Abstract Background: Arterial hypertension is a major public health problem and has increased considerably in young individuals in past years. Thus, identifying factors associated with this condition is important to guide intervention strategies in this population. Objective: To determine high blood pr...
