LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Hypothyroid offspring replacement with euthyroid wet nurses during lactation improves thyroid programming without modifying metabolic programming

ABSTRACT Objective Determine the milk quality effect during lactation on the metabolic and thyroid programming of hypothyroid offspring. Materials and methods Ten-week-old female Wistar rats were divided into two groups: euthyroid and thyroidectomy-caused hypothyroidism. The rats were matted and, one...

Effect of Fetal Hypothyroidism on Cardiac Myosin Heavy Chain Expression in Male Rats

Yousefzadeh, Nasibeh; Jeddi, Sajad; Alipour, Mohammad Reza.

Arq. bras. cardiol; 107 (2), 2016

Abstract Background: Thyroid hormone deficiency during fetal life could affect the cardiac function in later life. The mechanism underlying this action in fetal hypothyroidism (FH) in rats has not been elucidated thus far. Objective: The aim of this study is to evaluation the effect of FH on cardiac ...

Antitiroideos, Peso Corporal/efectos de los fármacos, Hipotiroidismo Congénito/sangre, Hipotiroidismo Congénito/inducido químicamente, Hipotiroidismo Congénito/metabolismo, ADN Complementario/metabolismo, Modelos Animales de Enfermedad, Frecuencia Cardíaca, Miocardio/metabolismo, Cadenas Pesadas de Miosina/metabolismo, Propiltiouracilo, ARN Mensajero/metabolismo, Distribución Aleatoria, Ratas Wistar, Tiroxina/sangre, Triyodotironina/sangre, Presión Ventricular

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