La enfermedad de Rosai-Dorfman se define como una histiocitosis de curso generalmente benigno, caracterizada por la acumulación ganglionar de histiocitos que presentan emperipolesis y positividad inmunohistoquímica para S-100 y CD68, y negatividad para CD1a y langerina. Su etiología exacta se desconoc...
Abstract: Light microscopy of granuloma annulare shows mucin deposition with lympho-histiocytic infiltrate. We describe the ultrastructural three-dimensional aspects of a typical case of granuloma with characteristic histopathological findings. At the ultrastructural level, affected collagen bundles and ...
ABSTRACT Hemosiderotic fibrohistiocytic lipomatous tumors are rare neoplasms that were first described in 2000. Initially considered a benign lipotamous lesion of the soft tissues, nowadays they are considered to be a locally aggressive tumor. They occur mainly in the foot and ankle of women in their fif...
Abstract: Rosai-Dorfman disease is a benign histiocytic proliferative disorder of unknown etiology. The disease mainly affects lymph node tissue, although it is rarely confined to the skin. Here, we describe a 53-year-old woman with purely cutaneous Rosai-Dorfman disease. The patient presented with a lar...
Abstract Histiocytoid Sweet's Syndrome is a rare inflammatory disease described in 2005 as a variant of the classical Sweet's Syndrome (SS). Histopathologically, the dermal inflammatory infiltrate is composed mainly of mononuclear cells that have a histiocytic appearance and represent immature myeloid ce...
Abstract Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clini...
Lepra Multibacilar/diagnóstico,
Síndrome de Sweet/diagnóstico,
Eritema/diagnóstico,
Histiocitos/patología,
Leprostáticos/uso terapéutico,
Lepra Multibacilar/complicaciones,
Lepra Multibacilar/tratamiento farmacológico,
Lepra Multibacilar/patología,
Neutrófilos/patología,
Prednisona/uso terapéutico,
Síndrome de Sweet/tratamiento farmacológico,
Síndrome de Sweet/etiología,
Síndrome de Sweet/patología,
Talidomida/uso terapéutico
Xantogranuloma é doença histiocítica, caracterizada por lesões amareladas na pele ou na derme, acompanhadas ou não de alterações hematológicas ou neoplasias. O objetivo deste é relatar o caso de uma mulher de 39 anos, com queixa de "inchaço" progressivo nas pálpebras superiores, há 6 anos, in...
El Sistema Retículo Endotelial (SRE), actualmente denominado Sistema Inmune Accesorio (SIA), está integrado por dos grupos celulares principales: 1- Células presentadoras de antígenos: Células Dendríticas; 2- Células procesadoras de antígenos: Macrófagos (o Histiocitos). Estas células están di...
