LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Molecular cloning and subcellular localization of six HDACs and their roles in response to salt and drought stress in kenaf (Hibiscus cannabinus L)

Wei, Fan; Tang, Danfeng; Li, Zengqiang; Kashif, Muhammad Haneef; Khan, Aziz; Lu, Hai; Jia, Ruixing; Chen, Peng.

Biol. Res; 52 (), 2019

BACKGROUND: Histone acetylation is an important epigenetic modification that regulates gene activity in response to stress. Histone acetylation levels are reversibly regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). The imperative roles of HDACs in gene transcription, trans...

Hibiscus/enzimología, Histona Acetiltransferasas/fisiología, Histona Desacetilasas/fisiología, Estrés Fisiológico/fisiología, Sequías, Hibiscus/crecimiento & desarrollo, Hibiscus/fisiología, Activación Transcripcional/fisiología, Reacción en Cadena en Tiempo Real de la Polimerasa, Clonación Molecular

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Mammalian histone acetyltransferase complexes

Over the last decade, great progress has been made in elucidating how the human genome operates in the chromatin context. This paper describes our work on two human acetyltransferases, PCAF and TIP60, and their interaction partners. This study provides new clues on the function of these enzymes. In a str...