LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis

Zhang, Xiaohao; Lu, Junying; Zhang, Qinghua; Luo, Qiang; Liu, Bin.

Biol. Res; 54 (), 2021

BACKGROUND: Atherosclerosis (AS) is the most common type in cardiovascular disease. Due to its complex pathogenesis, the exact etiology of AS is unclear. circRNA has been shown to play an essential role in most diseases. However, the underlying mechanism of circRNA in AS has been not understood clearly. ...

Aterosclerosis/genética, MicroARNs/genética, Apoptosis/genética, Histona Desacetilasa 1/genética, Proliferación Celular, Células Endoteliales de la Vena Umbilical Humana, Inflamación/genética, Lipoproteínas LDL, Proteínas Nucleares, ARN Circular, Transactivadores

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