Multiplex polymerase chain reaction as an improved method for screening Histoplasma capsulatum mating types
Mem. Inst. Oswaldo Cruz; 113 (10), 2018
Histoplasmosis is a systemic mycosis infection caused by Histoplasma capsulatum, a heterothallic ascomycete. The sexual reproduction of this fungus is regulated by the mating type (MAT1) locus that contains MAT1-1 and MAT1-2 idiomorphs, which were identified by uniplex polymerase chain reaction (PCR). Th...