Immunoexpression of TS, p53, COX2, EGFR, MSH6 and MLH1 biomarkers and its correlation with degree of differentiation, tumor staging and prognostic factors in colorectal adenocarcinoma: a retrospective longitudinal study
Säo Paulo med. j; 137 (1), 2019
ABSTRACT BACKGROUND: There are cases of colorectal tumors that, although small, show more aggressive evolution than large tumors. This motivated us to study whether there are any proteins capable of alerting about these changes. The aim here was to correlate the immunoexpression of the TS, p53, COX2, E...
Adenocarcinoma/mortalidad, Adenocarcinoma/patología, Biomarcadores de Tumor/análisis, Neoplasias Colorrectales/mortalidad, Neoplasias Colorrectales/patología, Ciclooxigenasa 2/análisis, Proteínas de Unión al ADN/análisis, Receptores ErbB/análisis, Inmunohistoquímica, Estimación de Kaplan-Meier, Estudios Longitudinales, Homólogo 1 de la Proteína MutL/análisis, Estadificación de Neoplasias, Modelos de Riesgos Proporcionales, Valores de Referencia, Estudios Retrospectivos, Timidilato Sintasa/análisis, Análisis de Matrices Tisulares, Proteína p53 Supresora de Tumor/análisis