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Relationship between vitiligo and Hashimoto’s thyroiditis

Andrade, Luís Jesuíno de Oliveira; Baptista, Gustavo Magno; Dias, Juliane Santos; Bittencourt, Alcina Maria Vinhaes; França, Larissa Santos.
Rev. Ciênc. Méd. Biol. (Impr.); 16 (1), 2017
Introduction: vitiligo is a multifactorial acquired depigmenting disorder, characterized by a spontaneous loss of functional melanocytes from the epidermis. Vitiligo and Hashimoto’s thyroiditis (HT) often occur in association and seem to be characterized by an autoimmune process. The vitiligo associate...
Vitíligo, Enfermedad de Hashimoto, Estudio Comparativo, Secuencia de Aminoácidos, Base de Datos, Peroxidasa, Homología de Secuencia de Aminoácido, Biología Computacional
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Sequence similarity between thyroid self-protein and hepatitis c virus polyprotein: possible triggering mechanism of autoimmune thyroiditis

Sousa, Maristella de Araújo Carvalho; Paraná, Raymundo; Andrade, Luís Jesuíno de Oliveira.
Arq. gastroenterol; 53 (3), 2016
ABSTRACT Background - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus and human proteins can activate autoimmun...
Autoantígenos/genética, Epítopos/genética, Técnicas de Genotipaje, Hepacivirus/genética, Hepacivirus/inmunología, Imitación Molecular/genética, Poliproteínas/genética, Homología de Secuencia de Aminoácido, Tiroiditis Autoinmune/inmunología, Tiroiditis Autoinmune/virología, Proteínas Virales/genética
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A novel lipocalin homologue from the venom gland of Deinagkistrodon acutus similar to mammalian lipocalins

Wei, C. B; Chen, J.
J. venom. anim. toxins incl. trop. dis; 18 (1), 2012
Lipocalins are involved in a variety of functions including retinol transport, cryptic coloration, olfaction, pheromone transport, prostaglandin synthesis, regulation of the immune response and cell homeostatic mediation. A full-length cDNA clone (named d-lipo), isolated from the venom gland cDNA library...
Lipocalinas/química, Venenos de Serpiente, Homología de Secuencia de Aminoácido, Biblioteca de Genes, Análisis de Secuencia de ADN, ARN Mensajero
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