Compression and evaluation of extended release matrix pellets prepared by the extrusion/spheronization process into disintegrating tablets
Braz. j. pharm. sci; 48 (1), 2012
In this study, a novel approach for compression of matrix pellets into disintegrating tablets has been studied in an attempt to overcome the issues pertaining to rupture of polymer coat during compression of reservoir-type pellets. Extended release matrix pellets were prepared by the extrusion/spheroniza...