A preformulation strategy for the selection of controlled-release components to simulate a subcutaneous implant
Bol. latinoam. Caribe plantas med. aromát; 19 (4), 2020
Many chronic diseases require repetitive injections as maintenance treatment. It is therefore important to investigate a possible alternative. A simulated subcutaneous implant prototype was fabricated as a polymer matrix covered by cylinder-shape tubing having a porous membrane. Sucrose, bovine serum alb...
Implantes de Medicamentos/metabolismo, Preparaciones de Acción Retardada, Técnicas In Vitro, Cromatografía Líquida de Alta Presión, Liofilización, 28574, Evaluación Preclínica de Medicamentos, Preparaciones Farmacéuticas/administración & dosificación, Tejido Subcutáneo, Proyectos Piloto, Liberación de Fármacos