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The case of eculizumab: litigation and purchases by the Brazilian Ministry of Health

Caetano, Rosângela; Rodrigues, Paulo Henrique Almeida; Corrêa, Marilena C Villela; Villardi, Pedro; Osorio-de-Castro, Claudia Garcia Serpa.
Rev. saúde pública (Online); 54 (), 2020
ABSTRACT OBJECTIVES This study examined the purchases of eculizumab, a high-cost monoclonal antibody used in the treatment of rare diseases by Brazilian federal agencies, in terms of purchased quantities, expenditures, and prices. METHODS Eculizumab purchases made between March 2007 and December 2018...
Anticuerpos Monoclonales Humanizados/economía, Brasil, Inactivadores del Complemento/economía, Control de Medicamentos y Narcóticos/legislación & jurisprudencia, Inactivadores del Complemento, Gobierno Federal, Agencias Gubernamentales, Gastos en Salud
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Treatment of hereditary angioedema due to C1 inhibitor deficiency in Argentina

Malbrán, Eloisa; Menéndez, Alejandra; Malbrán, Alejandro.
Medicina (B.Aires); 77 (4), 2017
The benefits of the worldwide approval of new drugs for the treatment of acute C1-INH-HAE attacks may still not reach all patients. Identifying the current barriers in the access to medication, as well as conducting a detailed assessment of the progress in this area, is essential to achieve universal tre...
Angioedemas Hereditarios/tratamiento farmacológico, Antiinflamatorios no Esteroideos/administración & dosificación, Argentina, Bradiquinina/administración & dosificación, Bradiquinina/análogos & derivados, Proteína Inhibidora del Complemento C1/administración & dosificación, Inactivadores del Complemento/administración & dosificación, Accesibilidad a los Servicios de Salud/estadística & datos numéricos, Encuestas y Cuestionarios
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