LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Eficácia hepatoprotetora do extrato metanólico de Indigofera suffruticosa (Mill) em lesão hepática induzido por paracetamol em camundongos

Lima, Izabela Rangel; Silva, Ivanise Brito; Lima, Roberta M Leite; Silva, Tainá M Santos; Maia, Maria B Sousa; Leite, Sônia Pereira.

Arq. gastroenterol; 56 (4), 2019

ABSTRACT BACKGROUND: Indigofera suffruticosa Mill (Fabaceae) is abundant in northeastern Brazil and popularly used in the treatment of infectious and inflammatory processes. Several biological properties, such as anti-inflammatory, anticancer, antitumor, hepatoprotective and low toxicity, are reported f...

Acetaminofén/toxicidad, Alanina Transaminasa/sangre, Analgésicos no Narcóticos/toxicidad, Aspartato Aminotransferasas/sangre, Bilirrubina/sangre, Enfermedad Hepática Inducida por Sustancias y Drogas/etiología, Enfermedad Hepática Inducida por Sustancias y Drogas/prevención & control, Indigofera/química, Extractos Vegetales/administración & dosificación, Sustancias Protectoras/administración & dosificación

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Indigofera suffruticosa Mill (Fabaceae): hepatic responses in mice bearing sarcoma 180

Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera suffrut...