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Avaliação da distribuição do mosaicismo cromossômico e dinâmica de replicação celular em pacientes com síndrome de Turner
Evaluation of the distribution of chromosomal mosaicism and dynamics of cellular replication in patients with Turner syndrome

Goulart, Miriam Beatriz.
Introdução: A Síndrome de Turner (ST) é uma das anomalias cromossômicas mais comuns, afetando uma em 2.500 nativivas. O cariótipo típico é o 45,X, seguido de anormalidades estruturais ou numéricas dos cromossomos X ou Y na forma universal ou em mosaico. Em razão da alta letalidade de fetos com ...
Mosaicismo, Síndrome de Turner/fisiopatología, Síndrome de Turner/etiología, Inestabilidad Cromosómica, Intercambio de Cromátides Hermanas, Hibridación Fluorescente in Situ, Ciclo Celular, Estudios Transversales
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Prognosis in colorectal cancer beyond TNM

Neves, Ana Lídia Ferreira; Barbosa, Laura Elisabete Ribeiro; Teixeira, João Paulo Meireles de Araújo.
J. coloproctol. (Rio J., Impr.); 40 (4), 2020
ABSTRACT Introduction: Colorectal cancer is one of the neoplasms with the greatest social impact. Given the great molecular heterogeneity and diversity of pathophysiological mechanisms, it is difficult to define prognostic factors that could guide therapy. Objectives: To identify the molecular prognost...
Neoplasias Colorrectales/diagnóstico, Carcinoma, Inestabilidad de Microsatélites, Inestabilidad Cromosómica, Biomarcadores, Pronóstico
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Current applications of molecular pathology in colorectal carcinoma

Gonzalez, Raul S; Washington, Kay; Shi, Chanjuan.
Appl. cancer res; 37 (), 2017
Molecular pathology is playing an increasingly important role in the treatment and overall management of patients with colorectal carcinoma. Three distinct genetic pathways have been identified that play a role in carcinogenesis: the chromosomal instability pathway, the microsatellite instability pathway...
Neoplasias Colorrectales/genética, Síndromes Neoplásicos Hereditarios, Patología Molecular, Carcinogénesis, Inestabilidad Cromosómica
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Genetic evaluation of mesenchymal stem cells by G-banded karyotyping in a Cell Technology Center

Borgonovo, Tamara; Vaz, Isadora May; Senegaglia, Alexandra Cristina; Rebelatto, Carmen Lucia Kuniyoshi; Brofman, Paulo Roberto Slud.
Rev. bras. hematol. hemoter; 36 (3), 2014
OBJECTIVE: To present the initial results of first three years of implementation of a genetic evaluation test for bone marrow-derived mesenchymal stem cells in a Cell Technology Center. METHODS: A retrospective study was carried out of 21 candidates for cell therapy. After the isolation of bone marrow mo...
Células Madre Mesenquimatosas, Citogenética, Inestabilidad Cromosómica, Cariotipificación
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