Prioritisation of potential drug targets against Bartonella bacilliformis by an integrative in-silico approach
Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND Carrion's disease (CD) is a neglected biphasic illness caused by Bartonella bacilliformis, a Gram-negative bacteria found in the Andean valleys. The spread of resistant strains underlines the need for novel antimicrobials against B. bacilliformis and related bacterial pathogens. OBJECTIVE T...
Antibacterianos/uso terapéutico, Infecciones por Bartonella/tratamiento farmacológico, Bartonella bacilliformis/efectos de los fármacos, Bartonella bacilliformis/genética, Bartonella bacilliformis/aislamiento & purificación, ADN Bacteriano/genética, ADN Bacteriano/aislamiento & purificación, Genómica, Reacción en Cadena de la Polimerasa