Objective: To evaluate the application of proactive pro-drug therapy (TDM) at week six in users of infliximab therapy in ulcerative colitis patients and to analyze the need for further disease optimization. Method: This is a retrospective analysis that will be carried out simultaneously at the Hospital d...
Inflammatory bowel disease (IBD) is a problem that directly affects the quality of life of patients suffering from this condition. Monitoring the serum level of infliximab (IFX) (TDM) is an important tool for guiding therapeutic decisions in IBD patients. The purpose of this study was to determine the si...
SUMMARY: Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, testosterone inhibition and apoptosis. Accordingly, this study was co...
Camellia sinensis/química,
Extractos Vegetales/farmacología,
Té/química,
Infliximab/farmacología,
Cisplatino/toxicidad,
Testículo/efectos de los fármacos,
Recuento de Espermatozoides,
Factor de Necrosis Tumoral alfa/antagonistas & inhibidores,
Apoptosis,
Estrés Oxidativo,
Inflamación,
Ratas Sprague-Dawley,
Extractos Vegetales/química,
Inmunohistoquímica,
Malondialdehído/análisis,
Glutatión/análisis,
Testículo/patología
Rationale: the use of anti-TNFα therapy, such as Infliximab (IFX), in patients with Chron’s disease (CD) can lead to changes in body composition. Objective: to evaluate the body composition and functional capacity of patients with CD. Method: Cross-sectional
study with patients with CD in clinical rem...
Besser, Nicolás;
Chacón, Erika;
Iglesias, Andrés;
Álvarez-Lobos, Manuel;
Pavez, Carolina;
Villalón, Constanza;
Urrejola, Gonzalo;
Zúñiga, Álvaro;
Molina, María Elena;
Miguieles, Rodrigo;
Bellolio, Felipe.
BACKGROUND: Treatment for moderate-severe active ulcerative colitis (UC) includes steroids, biologic therapy and total colectomy. Aim: To describe the features of patients with moderate to severe active UC, their hospital evolution and need for colectomy. MATERIAL AND METHODS: Non-concurrent cohort study...
Vedolizumabe e anticorpos anti-TNF-α (infliximabe, adalimumabe, certolizumabe pegol). Indicação: Tratamento pessoas com doença de Crohn com falha a um agente biológico anti-TNF-α em tratamento prévio. Pergunta: Para adultos com doença de Crohn moderada a grave com falha terapêutica para anticorp...
Objective: To determine the effectiveness and safety of infliximab and etanercept biosimilar drugs in patients diagnosed with rheumatoid arthritis, ankylosing spondylitis, ulcerative colitis, and psoriasis in a specialized institution in Colombia, between 2015 and 2019. Methods: A retrospective study in ...
Study Aim: The aim of the present study was to compare in real life the characteristics of treatment with infliximab according to the presence or absence of anoperineal involvement in Crohn's disease. Methods: We performed a single-center, prospective, non-interventional study, on patients with Crohn's d...
Infliximab,
Salud del Lactante,
Leche Humana,
Lactulosa,
Hipersensibilidad a las Drogas,
Exantema,
Urticaria,
Laxativos,
Loperamida,
Pancreatitis,
Gastroenterología,
Hormonas Tiroideas,
Hipotiroidismo
A doença de Crohn é uma patologia caracterizada pela inflamação transmural do trato gastrointestinal, compondo o espectro
das doenças inflamatórias intestinais. Nos casos mais graves,
dispõe de tratamento com uso de agentes biológicos e imunomoduladores que podem à reativação ou exacerbaçã...
