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Mieloma múltiple en Chile. Uso de drogas noveles en dos centros nacionales

Samaniego, Francisco; Bull, Leonardo; González, Néstor; Araos, Daniel; Rojas, Hernán; Donoso, Javiera; Marín, Arnaldo; Muñiz, María Sabrina; Castro, Ariel; Conte, Guillermo.
Rev. méd. Chile; 150 (3), 2022
BACKGROUND: The incorporation of novel drugs, such as proteasome inhibitors and immunomodulators, improved considerably the survival of patients with multiple myeloma. Aim: To evaluate the effect on survival of proteasome inhibitors and immunomodulators in patients with multiple myeloma in two national h...
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico, Bortezomib/uso terapéutico, Chile/epidemiología, Trasplante de Células Madre Hematopoyéticas, Mieloma Múltiple/diagnóstico, Inhibidores de Proteasoma/uso terapéutico, Trasplante Autólogo
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Evaluation of potential hepatotoxicity induced by Bortezomib

Mutluay, Duygu; Monsef, Yanad Abou; Tenekeci, Gözde Yücel.
Acta sci. vet. (Impr.); 49 (), 2021
Bortezomib, an inhibitor of 26S proteasome, is an anti-cancer therapeutic agent used in different cancer types. It leads to the arrest of the cancerous cell cycle by inhibiting angiogenesis and inducing apoptosis. Liver is the vital organ for detoxification and excretion of toxic products. The treatment ...
Ratones, Hígado/efectos de los fármacos, Bortezomib, Fenómenos Bioquímicos/efectos de los fármacos, Inhibidores de Proteasoma/uso terapéutico
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