LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Effects of ranibizumab and amfenac on the functional abilities and radiosensitivity of uveal melanoma cells

Bravo-Filho, Vasco; Logan, Patrick; Zoroquiain, Pablo; Aldrees, Sultan; Vilà, Natàlia; Oweida, Ayman; Belfort Neto, Rubens; Burnier Jr, Miguel N.

Arq. bras. oftalmol; 82 (1), 2019

ABSTRACT Purpose: To evaluate the effects of ranibizumab and amfenac in human uveal melanoma cell lines and to explore the ability of these compounds to sensitize uveal melanoma cells to radiation therapy. Methods: The 92.1 human uveal melanoma cell line was cultured and subjected to the proposed tre...

Inhibidores de la Angiogénesis/farmacología, Protocolos de Quimioterapia Combinada Antineoplásica, Línea Celular Tumoral, Movimiento Celular/efectos de los fármacos, Movimiento Celular/efectos de la radiación, Proliferación Celular/efectos de los fármacos, Proliferación Celular/efectos de la radiación, Inhibidores de la Ciclooxigenasa 2/farmacología, Relación Dosis-Respuesta en la Radiación, Melanoma/tratamiento farmacológico, Melanoma/radioterapia, Fenilacetatos/farmacología, Tolerancia a Radiación, Ranibizumab/farmacología, Reproducibilidad de los Resultados, Neoplasias de la Úvea/tratamiento farmacológico, Neoplasias de la Úvea/radioterapia

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Selective COX-2 Inhibitor (Meloxicam) and Tooth-Supporting Bone Quality. A Histomorphometric Study in Rats

Abstract The effects of the non-steroidal anti-inflammatory drugs (NSAIDs) on bone quantity and quality were investigated for years. However, there is lack of information on the impact of NSAIDs on the quality of tooth-supporting alveolar bone in absence of periodontal inflammation. Thus, the aim of this...