The outbreak of the novel coronavirus SARS-CoV-2 and the attendant physiological symptoms associated with the COVID-19 disease have led to an explosion of interest studying different aspects of the immune response. As of yet, the particular roles of natural killer cells are not well understood in this di...
En la actualidad existe un aumento del envejecimiento poblacional en Cuba y a nivel mundial, consecuencia del éxito de las políticas de salud pública y del desarrollo socioeconómico. Con el incremento progresivo de la edad se evidencian cambios en el sistema inmunológico que contribuyen a una suscep...
Abstract: Skin's innate immunity is the initial activator of immune response mechanisms, influencing the development of adaptive immunity. Some contact allergens are detected by Toll-like receptors (TLRs) and inflammasome NLR3. Keratinocytes participate in innate immunity and, in addition to functioning ...
Most human papillomavirus infections are readily cleared by the host immune response. However, in some individuals, human papillomavirus can establish a persistent infection. The persistence of high-risk human papillomavirus infection is the major risk factor for cervical cancer development. These viruse...
RESUMEN Introduction: Variants in genes encoding for HIV-1 co-receptors and their natural ligands have been individually associated to natural resistance to HIV-1 infection. However, the simultaneous presence of these variants has been poorly studied. Objective: To evaluate the association of single a...
Infecciones por VIH/epidemiología,
Infecciones por VIH/microbiología,
VIH-1/inmunología,
Haplotipos/genética,
Inmunidad Innata/inmunología,
Polimorfismo de Nucleótido Simple/genética,
Receptores CCR5/genética,
Estudios de Cohortes,
Colombia,
Genotipo,
Infecciones por VIH/genética,
VIH-1/química,
VIH-1/genética,
Inmunidad Innata/fisiología,
Fenotipo,
Polimorfismo de Nucleótido Simple/fisiología
Abstract: Inflammasomes are intracellular multiprotein complexes that comprise part of the innate immune response. Since their definition, inflammasome disorders have been linked to an increasing number of diseases. Autoinflammatory diseases refer to disorders in which local factors lead to the activatio...
As oncoproteínas E6 e E7 do Papilomavírus Humano (HPV) estão envolvidas na desregulação do sistema imune inato, provocando alterações na expressão dos receptores do tipo Toll (TLR). Considerando-se a função da via de sinalização iniciada por TLR, haveria uma vantagem para o vírus capaz de ma...
CONTEXTO: The metabolic syndrome is characterized by a clustering, in free-living populations, of cardiovascular and diabetes risk factors generally linked to insulin resistance, obesity and central obesity. Consonant with the well-established inflammatory pathogenesis of atherosclerotic disease, the met...
Diabetes Mellitus Tipo 2/inmunología,
Obesidad/inmunología,
Enfermedades Cardiovasculares/inmunología,
Mediadores de Inflamación,
Inmunidad Innata/inmunología,
Oportunidad Relativa,
Arteriosclerosis/etiología,
Factores de Riesgo,
Reacción de Fase Aguda,
Biomarcadores,
Citocinas/fisiología
