LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Cost-effectiveness of insulin analogs from the perspective of the Brazilian public health system

Cazarim, Maurílio de Souza; Rodrigues, João Paulo Vilela; Cruz-Cazarim, Estael Luzia Coelho da; Ayres, Lorena Rocha; Pereira, Leonardo Régis Leira.

Braz. J. Pharm. Sci. (Online); 53 (3), 2017

ABSTRACT Human insulin is provided by the Brazilian Public Health System (BPHS) for the treatment of diabetes, however, legal proceedings to acquire insulin analogs have burdened the BPHS health system. The aim of this study was to perform a cost-effectiveness analysis to compare insulin analogs and huma...

Insulinas/análisis, Análisis Costo-Beneficio/22074, Hemoglobina Glucada, Insulina de Acción Prolongada/análisis, Insulina de Acción Corta/análisis, Diabetes Mellitus/tratamiento farmacológico, Sistema Único de Salud/estadística & datos numéricos, Insulina/provisión & distribución, Costos y Análisis de Costo, Insulina Aspart/análisis, Insulina Detemir

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Insulin analogues versus human insulin in type 1 diabetes: direct and indirect meta-analyses of efficacy and safety

All patients with Diabetes Mellitus (DM) receive insulin therapy. In this study, we evaluated the efficacy, safety and tolerability of human insulin and insulin analogues. We performed a systematic review of the literature and a meta-analysis according to the Cochrane Collaboration methodology. In the ab...