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Herbal-drug interaction through the pregnane X receptor

de Barros, Yuri Yabu; Carneiro, Amanda A; Sinoti, Simone Batista Pires; Sampaio, María Isadora Gabriel; Magalhães, Pérola Oliveira; Silveira, Damaris; Simeoni, Luiz Alberto; Fonseca-Bazzo, Yris Maria.
Bol. latinoam. Caribe plantas med. aromát; 22 (3), 2023
The interaction potential of Cynara scolymus L., Mikania glomerata Spreng.,Rhamnus purshiana DC and Uncaria tomentosa (Willd. Ex Roem. & Schult.) with conventional drugs metabolized by the CYP3A4 metabolic route was tested in HeLa cell lines, using the in vitro model of the hPXR. The herbal medicin...
Interacciones de Hierba-Droga, Cynara scolymus, Mikania, Rhamnus, Uña de Gato, Técnicas In Vitro, Inductores del Citocromo P-450 CYP3A/química, Plantas Medicinales
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The dietary supplement of Ginkgo biloba: a comprehensive review of its potential interactions based on pre-clinical and clinical evidences

Ahmad, Rizwan; Alsadah, Hawra Adnan; Riaz, Muhammad; AlLehaibi, Lina Hussain; Alraya, Reem Ahmed; Aljamea, Ahmed; Zahoor, Saira.
Bol. latinoam. Caribe plantas med. aromát; 20 (6), 2021
This review present Gingko biloba (GB) interactions, based on clinical and pre-clinical presentations. Literature was retrieved using databases; ScienceDirect, PubMed, Google scholar, Web of Science, Scopus etc. 14/45 interactions were found with clinical presentations. More interactions (80%) were repo...
Interacciones de Hierba-Droga/fisiología, Suplementos Dietéticos, Ginkgo biloba, Extractos Vegetales/farmacocinética, Extractos Vegetales/efectos adversos
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Jugos de fruta y productos herbáceos como perpetradores de interacciones farmacocinéticas mediadas por enzimas metabolizadoras y transportadores de membrana. Relevancia en clínica

Cortés, Matías; Díaz, Rodrigo; Verdugo, Samuel; Cabrera, Salvador; Torres-Vergara, Pablo.
Rev. méd. Chile; 149 (7), 2021
Drug disposition in the human body is strongly influenced by transporters and metabolizing enzymes expressed in key organs including intestine, liver and kidney. Since drugs and chemicals present in foods such as fruit juices and herb-based products are substrates of the above-mentioned proteins, there i...
Jugos de Frutas y Vegetales, Preparaciones de Plantas/efectos adversos, Interacciones de Hierba-Droga, Frutas
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