Results: 8

Low frequency of regulatory B-cells and increased CD4+ and CD8+ interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type

Abstract INTRODUCTION: Tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) is a disease caused by human T-cell lymphotropic virus type 1 (HTLV-I) that mainly infects CD4 T cells-for example, those of the CD4+CD25hiFOXP3+ [Treg] phenotype-where it inhibits forkhead box protein P3 (FOXP3)...

Evaluation of the profile of inflammatory cytokines, through immunohistochemistry, in the skin of patients with allergic contact dermatitis to nickel in the acute and chronic phases

An. bras. dermatol; 93 (6), 2018
Abstract: Background: Allergic contact dermatitis to ion nickel (Ni+2) is an inflammatory dermatosis, common in industrialized countries. It involves the activation of nickel-specific T-cells, followed by proliferation and induction of a mixed profile of both proinflammatory and regulatory cytokines, su...

Histopathologic aspects of experimental cysticercosis and in situ cytokines profile in C57BL/6 mice

Arq. neuropsiquiatr; 76 (5), 2018
ABSTRACT Neurocysticercosis (NCC) is one of the parasitic infections that most affects the central nervous system. The knowledge regarding its immunopathogenesis and pathophysiology needs broadening. Taenia crassiceps cysticerci are used as the NCC experimental model. The aim of this work was to describe...

Social conditions and immune response in human immunodeficiency virus-seropositive pregnant women: a cross-sectional study in Brazil

Abstract INTRODUCTION The functioning of the immune system during pregnancy is altered in both human immunodeficiency virus (HIV)-infected and uninfected women. Unfavorable socioeconomic conditions have been indicative of higher morbidity and mortality and worsening of the immune system. The aim of thi...

Humoral and cellular immune response of mice challenged with Yersinia pestis antigenic preparations

Braz. j. infect. dis; 21 (6), 2017
ABSTRACT Objectives: The plague, which is an infectious disease caused by Yersinia pestis, still threatens many populations in several countries. The worldwide increase in human plague cases and the potential use of the bacteria as a biological weapon reinforce the need to study the immunity that is ind...

Lactobacillus rhamnosus could inhibit Porphyromonas gingivalis derived CXCL8 attenuation

J. appl. oral sci; 24 (1), 2016
ABSTRACT An increasing body of evidence suggests that the use of probiotic bacteria is a promising intervention approach for the treatment of inflammatory diseases with a polymicrobial etiology. P. gingivalis has been noted to have a different way of interacting with the innate immune response of the hos...

Producción de interferón-gamma e interleuquina 4 por células mononucleadas de sangre periférica infectadas con virus respiratorio sincicial y adenovirus
Interferon-gamma and interleukin-4 production by respiratory synctytial virus and adenovirus infected peripheral blood mononuclear cells

Las infecciones respiratorias por virus respiratorio sincicial (VRS) y adenovirus (Ad) son la principal causa de morbimortalidad entre las infecciones respiratorias agudas bajas (RAB) de la infancia. Ambos virus pueden dejas secuelas, al VRS se le ha atribuido desencadenar obstrucción bronquial persiste...

Modelo sobre la relación parásito-respuesta inmunológica del hospedador en la leishmaniasis cutánea americana humana

Los objetivos del siguiente trabajo son: 1.- Evaluar la existencia de un mecanismo de regulación de la respuesta inmunológica dependiendo de las prostaglandinas y sensible a la indometacina, en pacientes con alguna de las tres formas clínicas de la leishmaniasis cutánea americana (Capítulo 1). 2.- E...