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Poly-ε -caprolactone microspheres containing interferon alpha as alternative formulations for the treatment of chronic hepatitis C

Braz. j. pharm. sci; 48 (1), 2012
Interferon-alpha (IFN-alpha) is one of the main drugs used in the treatment of hepatitis C. Use of IFN-alpha has some limitations that result in poor treatment efficacy and low patient compliance. Therefore, the aim of this study was to develop poly-ε-caprolactone (PCL) microspheres containing IFN-a...