Objetivo: investigar a associação entre o polimorfismo do tipo VNTR, do gene IL4, localizado
na região do intron 3, em pacientes diagnosticados com acidente vascular encefálico
hemorrágico (AVEH) ou aneurisma intracerebral em uma amostra do Distrito Federal. Método:
Tratou-se de um estudo observaci...
Objetivo: Associar a presença do SNP IL1B -511 (rs16944) à susceptibilidade ao CPT, bem como
comparar níveis séricos da citocina antes e sete dias após a Iodoterapia, juntamente com outras
características clínicas dos pacientes. Método: Trata-se de um estudo caso-controle, no qual
foram obtidas a...
Abstract INTRODUCTION Suckling by schistosomotic mice improves anti-ovalbumin (OA) antibody production, while delayed-type hypersensitivity (DTH) remains unaffected. This property of milk from schistosomotic mice was investigated in IL-12/IL-23-deficient mice (IL-12p40KO). METHODS We compared anti-OA...
Olano, Carolina;
López, Virginia;
Freire, Teresa;
Rodríguez, Ximena;
Pontet, Yessica;
Alemán, Alicia;
Rodríguez, Natalia;
Rovira, Laura;
Trucco, Elena;
Osinaga, Eduardo;
Cohen, Henry;
Quigley, Eamonn MM.
ABSTRACT Background: Evidence indicates that low-grade inflammation can alter gastrointestinal motor and sensory function and might contribute to the genesis of symptoms in IBS. Objective: To examine relationships between IBS, disease antibodies and cytokine titers in celiac patients and a control gr...
Costa, Allyson Guimarães;
Chaves, Yury Oliveira;
Teixeira-Carvalho, Andréa;
Ramasawmy, Rajendranath;
Antonelli, Lis Ribeiro Valle;
Barbosa, Lucas;
Balieiro, Antonio;
Monteiro, Wuelton Marcelo;
Mourão, Maria Paula;
Lacerda, Marcus Vinicius Guimarães;
Martins-Filho, Olindo Assis;
Costa, Fabio Trindade Maranhão;
Malheiro, Adriana;
Nogueira, Paulo Afonso.
BACKGROUND Thrombocytopenia in malaria involves platelet destruction and consumption; however, the cellular response underlying this phenomenon has still not been elucidated. OBJECTIVE To find associations between platelet indices and unbalanced Th1/Th2/Th17 cytokines as a response to thrombocytopenia...
Interleucina-12/sangre,
Interleucina-2/sangre,
Subgrupos Linfocitarios/inmunología,
Malaria Vivax/sangre,
Malaria Vivax/inmunología,
Malaria Vivax/parasitología,
Malaria Vivax/patología,
Plasmodium vivax/inmunología,
Trombocitopenia/sangre,
Trombocitopenia/parasitología,
Trombocitopenia/patología
ABSTRACT BACKGROUND: Gastric adenocarcinoma is the fourth most common cause of cancer-associated death worldwide. OBJECTIVE: We evaluated the immunological status of patients with gastric cancer before surgery and circulating cytokines as potential diagnostic biomarkers for gastric cancer. METHODS: ...
Adenocarcinoma/sangre,
Adenocarcinoma/diagnóstico,
Biomarcadores de Tumor/sangre,
Estudios de Casos y Controles,
Ensayo de Inmunoadsorción Enzimática,
Interleucina-10/sangre,
Interleucina-12/sangre,
Interleucina-2/sangre,
Persona de Mediana Edad,
Neoplasias Gástricas/sangre,
Neoplasias Gástricas/diagnóstico
The impact of food restriction (FR) during 56 days on serum levels of cytokines in mice fed a high-fat diet (HFD) or high-carbohydrate diet (HCD) were evaluated. The amount of food was reduced 50% for HFD-FR and HCD-FR groups compared to mice receiving free access to HFD (HFD group) or HCD (HCD group). W...
Fenómenos Fisiológicos Nutricionales de los Animales/fisiología,
Biomarcadores/sangre,
Peso Corporal,
Restricción Calórica/métodos,
Citocinas/sangre,
Dieta de Carga de Carbohidratos/métodos,
Dieta Alta en Grasa/métodos,
Privación de Alimentos/fisiología,
Inmunoensayo/métodos,
Interleucina-12/sangre,
Valores de Referencia,
Factores de Tiempo
The mosquito midgut is the organ into which the blood meal passes and in which, within a peritrophic membrane secreted by the epithelium, the blood is retained during digestion and absorption. The mosquito midgut is lined with an actin filled microvilli that are exposed to the harsh environment of the gu...
Tracto Gastrointestinal/patología,
Epitelio/patología,
Culicidae,
Ratones Endogámicos BALB C,
Tracto Gastrointestinal/inmunología,
Epitelio/inmunología,
Anopheles,
Mucina-1,
Interleucina-12,
Microscopía/métodos,
Digestión
There is an interest in the use of IL-12 as a possible anti-cancer drug to induce immune responses and anti-IL-13 formulations to treat the undesirable effects of IL-13. Thus, the present study aimed at analyzing IL-12 and IL-13 profiles, viral hepatitis serology and blood cultures in acute myeloid leuke...