Cui, Xinyuan;
Li, Yifu;
Yuan, Shuguang;
Huang, Yao;
Chen, Xiaojun;
Han, Yachun;
Liu, Zhiwen;
Li, Zheng;
Xiao, Yang;
Wang, Youliang;
Sun, Lin;
Liu, Hong;
Zhu, Xuejing.
BACKGROUND: Alpha-kinase 1 (ALPK1) is a master regulator in inflammation and has been proved to promote renal fibrosis by promoting the production of IL-1β in diabetic nephropathy (DN) mice. Pyroptosis is involved in high glucose (HG)-induced tubular cells injury, characterized by activation of Gasdermi...
ABSTRACT Objective: Our aim was to analyze levels of proinflammatory biomarker interleukin-18 (IL-18) in healthy controls and patients with polycystic ovary syndrome (PCOS) focusing on its association with obesity, clinical, hormonal, and metabolic characteristics. Subjects and methods: Fifty-eight pat...
Abstract Background: Migraines are headaches caused by changes in the trigeminovascular metabolic pathway. Migraine headache attacks are associated with neurovascular inflammation, but their pathophysiological mechanisms have not been fully explained. Objective: To investigate the relationship between ...
O líquen plano oral (LPO) é uma condição imuno-inflamatória mucocutânea crônica que ainda possui etiologia e patogênese desconhecidas. Estudos mostrando a participação de citocinas no LPO, em especial, interleucinas (IL)-6, IL-17 e IL-18, são escassos, assim como a correlação das caracterís...
Resumo Fundamento A insuficiência coronariana constitui a principal causa de morte no mundo, e a identificação de pacientes de maior risco para doença arterial coronariana (DAC) constitui um desafio. Objetivos Testar os biomarcadores interleucina 18 (IL-18) e proteína precursora do trombo (TpP),...
INTRODUCCIÓN: Al momento se tienen propuestas de tratamiento para el COVID-19, en las que se incluye el uso de interferón (Lu 2020; Li and De Clercq 2020). Dentro del espectro de los medicamentos catalogados como interferón (IFN) tenemos IFN alfa o IFN alfa pegilado, IFN alfa 2a, IFN alfa 2b, IFN beta...
ABSTRACT Host immunogenetic setting is involved in the regulation of human papillomavirus (HPV) infection and development of condyloma acuminatum (CA). We investigated the correlation of two common single nucleotide polymorphisms (SNPs) (−607C/A and −137G/C) of IL-18 with the susceptibility o...
Alelos,
Pueblo Asiatico/genética,
China,
Estudios de Cohortes,
Condiloma Acuminado/genética,
Condiloma Acuminado/virología,
Predisposición Genética a la Enfermedad,
Genotipo,
Interleucina-18/genética,
Infecciones por Papillomavirus/complicaciones,
Infecciones por Papillomavirus/transmisión,
Polimorfismo Genético,
Polimorfismo de Nucleótido Simple/genética,
Regiones Promotoras Genéticas
ABSTRACT Objective The present study compares immune and endocrine parameters between HIV-infected patients who underwent the Immune Reconstitution Inflammatory Syndrome (IRIS-P) during antiretroviral therapy (ART) and HIV-patients who did not undergo the syndrome (non-IRIS-P). Materials and methods Bl...
Terapia Antirretroviral Altamente Activa/efectos adversos,
Biomarcadores/sangre,
Relación CD4-CD8,
Sulfato de Deshidroepiandrosterona/sangre,
Ensayo de Inmunoadsorción Enzimática,
Infecciones por VIH/sangre,
Infecciones por VIH/tratamiento farmacológico,
Infecciones por VIH/inmunología,
Infecciones por VIH/metabolismo,
Hidrocortisona/sangre,
Síndrome Inflamatorio de Reconstitución Inmune/sangre,
Síndrome Inflamatorio de Reconstitución Inmune/inmunología,
Síndrome Inflamatorio de Reconstitución Inmune/metabolismo,
Interleucina-18/sangre,
Interleucina-6/sangre,
Luminiscencia,
Estudios Prospectivos,
Tiroxina/sangre,
Carga Viral
