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Therapeutic effects of benzoylaconitine and paeoniflorin in rats with collagen-induced arthritis

Li, Jie; Gu, Ping; Tong, Rong-Sheng; Wang, JiaFeng; Zhang, ShuHan; He, Dan; Li, Jin-Qi.
Braz. J. Pharm. Sci. (Online); 58 (), 2022
Abstract To explore the effects and mechanisms of benzoylaconitine and paeoniflorin on collagen-induced arthritis (CIA) rats. Weight, paw swelling, arthritis index and joint pathologic changes were examined in each group after CIA induction. PGE2, IL-1β, IL-6, IL-10, TNF-α, VEGF, MMP-3, IgG and anti-CI...
Artritis Experimental/inducido químicamente, Usos Terapéuticos, Microscopía Electrónica de Transmisión/métodos, Dinoprostona/efectos adversos, Ensayo de Inmunoadsorción Enzimática/métodos, Interleucina-1/farmacología, Interleucina-10/farmacología, Interleucina-6/farmacología, Metaloproteinasas de la Matriz
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Evaluation of the effects of erythropoietin and interleukin-6 in rats submitted to acute spinal cord injury

Barros, Alderico Girão Campos de; Cristante, Alexandre Fogaça; Santos, Gustavo Bispo dos; Natalino, Renato José Mendonça; Ferreira, Ricardo José Rodriguez; Barros-Filho, Tarcísio Eloy Pessoa de.
Clinics; 74 (), 2019
OBJECTIVE: To evaluate the effects of interleukin-6 (IL-6) and erythropoietin (EPO) in experimental acute spinal cord injury (SCI) in rats. METHODS: Using standardized equipment, namely, a New York University (NYU) Impactor, a SCI was produced in 50 Wistar rats using a 10-g weight drop from a 12.5-mm he...
Modelos Animales de Enfermedad, Eritropoyetina/farmacología, Eritropoyetina/uso terapéutico, Potenciales Evocados Motores/efectos de los fármacos, Interleucina-6/farmacología, Interleucina-6/uso terapéutico, Fármacos Neuroprotectores/farmacología, Ratas Wistar, Recuperación de la Función/efectos de los fármacos, Traumatismos de la Médula Espinal/tratamiento farmacológico, Traumatismos de la Médula Espinal/patología
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Effect of intraoperative intravenous lidocaine on pain and plasma interleukin-6 in patients undergoing hysterectomy

Oliveira, Caio Marcio Barros de; Sakata, Rioko Kimiko; Slullitel, Alexandre; Salomão, Reinaldo; Lanchote, Vera Lucia; Issy, Adriana Machado.
Rev. bras. anestesiol; 65 (2), 2015
BACKGROUND AND OBJECTIVES: Interleukin-6 is a predictor of trauma severity. The purpose of this study was to evaluate the effect of intravenous lidocaine on pain severity and plasma interleukin-6 after hysterectomy. METHOD: A prospective, randomized, comparative, double-blind study with 40 patients, aged...
Histerectomía/instrumentación, Lidocaína/farmacología, Interleucina-6/farmacología, Dolor Postoperatorio, Administración Intravenosa/instrumentación, Estudios Prospectivos
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Anti-inflammatory components of the Vietnamese starfish Protoreaster nodosus

Thao, Nguyen Phuong; Luyen, Bui Thi Thuy; Koo, Jung Eun; Kim, Sohyun; Koh, Young Sang; Cuong, Nguyen Xuan; Nam, Nguyen Hoai; Van Kiem, Phan; Kim, Young Ho; Van Minh, Chau.
Biol. Res; 48 (), 2015
BACKGROUND: In the present study, we examined the inhibitory effects of a methanolic extract, dichloromethane fraction, water layer, and polyhydroxylated sterols (1-4) isolated from the Vietnamese starfish Protoreaster nodosus on pro-inflammatory cytokine (IL-12 p40, IL-6, and TNF-α) production in LPS-s...
Antiinflamatorios/análisis, Células Dendríticas/efectos de los fármacos, Subunidad p40 de la Interleucina-12/farmacología, Interleucina-6/farmacología, Estrellas de Mar/química, Factor de Necrosis Tumoral alfa/farmacología, Supervivencia Celular/efectos de los fármacos, Subunidad p40 de la Interleucina-12/análisis, Interleucina-6/análisis, Esteroides/administración & dosificación, Factor de Necrosis Tumoral alfa/análisis, Ensayo de Inmunoadsorción Enzimática, Concentración 50 Inhibidora, Lipopolisacáridos, Ratones Endogámicos C57BL, Cultivo Primario de Células, Vietnam
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