Abstract This study aimed to investigate the molecular mechanism of Picrasma quassioides Benn against inflammation by means of network pharmacology. The paper will provide a reference for multi-target and multi-channel treatment of inflammation with traditional Chinese medicine. Through screening and ana...
Abstract Someoxoquinoline-acylhydrazonederivativesshowedactivityagainst HumanImmunodeficiency Virus type 1 (HIV-1). These compounds must also be active against Herpes Simplex Virus type 1 (HSV-1) by an inhibition mechanism where they interact with the HSV-DNA-polymerase/DNA-duplex complex. There are seve...
Abstract TCMSP platform of systematic pharmacology of traditional Chinese medicine This study aimed to investigate the molecular mechanism of Fructus Ligustri Lucidi (NZZ, Chinese abbreviation) against osteoporosis (OP) by means of network pharmacology.ChemDraw Professional 15.1 software and Molinspirati...
Investigación/clasificación,
Ligustrum/efectos adversos,
Osteoporosis/patología,
Medicina Tradicional China,
Farmacología en Red/instrumentación,
Factor de Necrosis Tumoral alfa/farmacología,
Genes,
Interleucina-17/análogos & derivados,
Ontología de Genes,
Pueblos del Este de Asia,
Productos Finales de Glicación Avanzada/efectos adversos,
Programas Informáticos/clasificación
Abstract Existing medications i.e. the antipsychotic drugs are known to be effective in treating only the positive symptoms of schizophrenia, while being ineffective on negative and cognitive symptoms of the disease. In addition, these medications cause extrapyramidal symptoms, forcing many patients towa...
Abstract Recently, the world has coped with the challenge of the novel SARS-CoV-2 rapid spreading, causing COVID-19. This scenario has overburdened health systems, forced social isolation, and interrupted some services, changing the way how health assistance is provided. The management of chronic infecti...
Malaria is nowadays one of the most serious health concerns in a global scale and, although there is an evident increase in research studies in this area, pointed by the vast number of hits and leads, it still appears as a recurrent topic every year due to the drug resistance shown by the parasite exposi...
El presente artículo pretende abonar el debate sobre la delimitación y alcance de lo que en algunos informes de investigación y en la bibliografía existente se ha nominado como investigación teórica o investigación conceptual. Aunque varios autores hacen referencia a este tipo de investigaciones h...
RESUMEN Introducción: los profesionales dedicados a la medicina natural y tradicional deben establecer y divulgar las evidencias científicas para su uso adecuado y seguro. Objetivos: identificar artículos científicos relacionados con investigaciones clínicas sobre medicina natural y tradicional ...
Introducción: En la práctica de la conservación biológica, a menudo se necesita de información científica para guiar las decisiones de manejo, pero esta información es especialmente escasa en áreas marinas protegidas. Las áreas marinas protegidas enfrentan el desafío de proteger especies pelág...
o Introduction: Freshwater research in Latin America has been increasing in recent years, with a large participation of scientists based on local institutions. However, researchers in the region are facing diverse challenges, and we lack a regional overview of the status of freshwater research. Objective...
