LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Protective effects of Baicalin injection on severe acute pancreatitis through regulating follistatin-like-1 signaling pathway by down-regulating miR-429 expression in mice

Li, Hui; Yang, Wei; Liu, Ming-wei; Wan, Lin-jun; Wang, Yan-qiong.

Braz. J. Pharm. Sci. (Online); 58 (), 2022

Abstract In China, Scutellaria is used for treating inflammatory-related diseases. Baicalin is the main active component of Scutellaria and has protective effects on acute pancreatitis. However, the mechanism of Baicalin is still unclear. In this study, the protective effects of baicalin on acute pancrea...

Scutellaria/efectos adversos, Pancreatitis/patología, Proteína HMGB1/efectos adversos, Ensayo de Inmunoadsorción Enzimática/instrumentación, Folistatina/administración & dosificación, Hígado/anomalías, Inyecciones/clasificación, Receptores del Factor de Necrosis Tumoral, Western Blotting

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Comparative application of biological and ninhydrin- derivatized spectrophotometric assays in the evaluation and validation of amikacin sulfate injection

Abstract Instrumental techniques are preferred over bioassay methods for antibiotic quantification mainly due to speed and ability to quantify metabolites in biological samples; however, the potency and biological activity of these drugs cannot be assessed. Two methods - agar well diffusion (bio-assay) a...