Results: 3

Mechanical properties and immunotherapeutic effects of dissolving microneedles with different drug loadings based on hyaluronic acid

Abstract Improving vaccine immunity and reducing antigen usage are major challenges in the clinical application of vaccines. Microneedles have been proven to be painless, minimally invasive, highly efficient, and have good patient compliance. Compared with traditional transdermal drug delivery, it can e...

Heparin induced bullous hemorrhagic dermatosis at a site distant from the injection. A report of five cases

An. bras. dermatol; 91 (6), 2016

Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site

An. bras. dermatol; 91 (5,supl.1), 2016
Abstract Cutaneous reactions associated with interferons (IFNs) treatment are either localized or generalized. The most common presentation of localized reactions at IFNs injection site is usually an erythematous patch or plaque. Local leukocytoclastic vasculitis presenting with cutaneous necrosis is ext...