Results: 36

Interleukin-37 has A Promising Cardioprotective Effect on Isoproterenol-Induced Myocardial Infarction

Int. j. morphol; 41 (5), 2023
SUMMARY: The main cause of mortality and disability globally is myocardial infarction (MI). Isoproterenol (ISO), a β-adrenoceptor agonist, has been used to induce rat myocardial necrosis. Whereas interleukin-37 (IL-37) has anti-inflammatory and cytoprotective properties. The study aimed to investiga...

Medição automática de valva mitral a partir de ecocardiograma utilizando processamento digital de imagens

ABC., imagem cardiovasc; 36 (1), 2023
Fundamento: A avaliação da área valvar mitral por meio da reconstrução multiplano na ecocardiografia tridimensional é restrita a softwares específicos e à experiência dos ecocardiografistas. Eles precisam selecionar manualmente o frame do vídeo que contenha a área de abertura máxima da valva ...

Pediatric patients head-up-tilt-test with pharmacological challenge, it is safe?

Arch. cardiol. Méx; 90 (2), 2020
Abstract Syncope in pediatrics represents an important cause of visits to the emergency units. For this reason, excluding a cardiac or malignant origin is essential at the time of the initial approach to determine what is the next step in management, or if they need to be referred to a pediatric cardiolo...

Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways

Braz. j. med. biol. res; 53 (2), 2020
Aliskiren (ALS) is well known for its antihypertensive properties. However, the potential underlying the molecular mechanism and the anti-hypertrophic effect of ALS have not yet been fully elucidated. The aim of the present study was to investigate the role of ALS in mammalian target of rapamycin (mTOR) ...

Papel dos receptores β1 e β2 adrenérgicos sobre a diferenciação osteoblástica de células mesenquimais estromais da medula óssea de ratos espontaneamente hipertensos

Introdução: O remodelamento ósseo é um processo complexo que depende do balanço entre formação e reabsorção óssea, mecanismo regulado pelas células ósseas e fatores sistêmicos, como o Sistema Nervoso Simpático (SNS). Os mediadores deste sistema são capazes de regular o metabolismo ósseo a...

Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced by ischemia and reperfusion

Acta cir. bras; 34 (5), 2019
Abstract Purpose: To evaluate the cardioprotective response of the pharmacological modulation of β-adrenergic receptors (β-AR) in animal model of cardiac ischemia and reperfusion (CIR), in spontaneously hypertensive (SHR) and normotensive (NWR) rats. Methods: CIR was induced by the occlusion...

Primary Ventricular Fibrillation in a Patient with Mild Hypercalcemia

Arq. bras. cardiol; 110 (4), 2018

Intraoperative awareness as an example of the influence of cardiac output on anesthetic dosing: case report

Rev. colomb. anestesiol; 46 (4), 2018
Abstract A case of intraoperative awareness during ablation of pulmonary veins-one of the most widely used techniques in interventional cardiology-is discussed. An infusion of isoproterenol was administered following the ablation of ectopic foci. A few seconds after the infusion the patient experienced i...

Cocaine long-term administration induces myocardial depressant effects and adrenoceptors desensitization

Acta cient. venez; 53 (3), 2002
Cocaine as a drug of abuse can cause many cardiovascular toxic effects. The objective of this work was to study the mechanism of the negative inotropic effect of cocaine on isolated right ventricle strips and its relationship with myocardial catecholamines desensitization after long- term cocaine adminis...

Modulaçäo do estresse oxidativo em glândulas submandibulares de rato

As espécies reativas de oxigênio geradas in vivo têm sido implicadas em vários mecanismos como apoptose, crescimento e diferenciação celular, câncer e inflamação. O estresse oxidativo é o produto do desbalanço entre os agentes pro-oxidantes e antioxidantes celulares, causando danos por meio da...