LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Pin1 aggravates renal injury induced by ischemia and reperfusion in rats via Nrf2/HO-1 mediated endoplasmic reticulum stress

Yu, Honglin; Jiang, Guanjun; Hu, Wei; Xu, Changgeng.

Acta cir. bras; 37 (1), 2022

Purpose: To investigate the role of peptidyl-prolyl cis/trans isomerase 1 (Pin1) on renal ischemia-reperfusion (I/R) injury and underlying mechanism. Methods: By establishing the in vitro and in vivo models of renal I/R, the role of Pin1 was explored by using molecular assays. Results: In renal I/R, en...

Peptidilprolil Isomerasa de Interacción con NIMA/análisis, Isquemia/veterinaria, Factor 2 Relacionado con NF-E2/análisis, Hemo-Oxigenasa 1, Estrés del Retículo Endoplásmico, Reperfusión/veterinaria, Ratas Sprague-Dawley

Fulltext

Allogenic mesenchymal stem cell intravenous infusion in reparation of mild intestinal ischemia/reperfusion injury in New Zealand rabbits

Oliveira, Alvaro P. L; Rangel, Julia P. P; Raposo, Viviane; Pianca, Noely G; Cruz, Emanuelle P; Pereira Neto, Evandro; Fiorio, Wagner A. B; Monteiro, Betânia S.

Pesqui. vet. bras; 38 (4), 2018

The present study aimed to evaluate the efficacy of mesenchymal stem cell (MSC) infusion, derived from adipose tissue, on reduction of local and remote tissue damage caused by the event of experimental intestinal I/R in New Zealand breed rabbits. For obtaining, characterization, and cultivation of MSC de...

Conejos/genética, Conejos/anatomía & histología, Infusiones Intravenosas/veterinaria, Trasplante de Células Madre Mesenquimatosas/22074, Conejos/lesiones, Isquemia/veterinaria

Fulltext

Laminar lesions in horses with systemic oxidative stress, committed by experimentally induced or naturally occurring gastrointestinal disorders

Laskoski, Luciane M; Locatelli-Dittrich, Rosangela; Sousa, Renato S; Brum, Juliana S; Cristo, Thierry G; Montiani-Ferreira, Fabiano; Beltrame, Olair C; Valadão, Carlos A. A.

Pesqui. vet. bras; 36 (8), 2016

Laminitis in horses can be associated with lesions in multiple organs secondary to sepsis. Twenty-one horses suffering from gastrointestinal disorders were used in the experiment; 7 horses with experimentally induced endotoxemia and intestinal ischaemia, and 14 horses suffering from naturally occurring c...

Caballos/lesiones, Pezuñas y Garras/lesiones, Pezuñas y Garras/patología, Estrés Oxidativo, Endotoxemia/veterinaria, Isquemia/veterinaria, Sepsis/veterinaria, Enfermedades Gastrointestinales/veterinaria, Cólico/veterinaria, Ácido Peroxinitroso, Superóxido Dismutasa

Fulltext