LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

The role of ischemic preconditioning in the expression of apoptosis-related genes in a rat model of intestinal ischemia-reperfusion injury

Miranda, Celina Teresa Castelo Branco Couto de; Fagundes, Djalma José; Miranda, Edinaldo de; Simões, Ricardo Santos; Carbonel, Adriana Aparecida Ferraz; Florencio-Silva, Rinaldo; Taha, Murched Omar.

Acta cir. bras; 34 (5), 2019

Abstract Purpose: To analyze the effects of ischemic preconditioning (IPC) in the expression of apoptosis-related genes in rat small intestine subjected to ischemia and reperfusion. Methods: Thirty anesthetized rats underwent laparotomy and were drive into five groups: control (CG); ischemia (IG); is...

Apoptosis/genética, Proteínas Reguladoras de la Apoptosis/análisis, Proteínas Reguladoras de la Apoptosis/genética, Constricción, Regulación hacia Abajo, Células Endoteliales/patología, Expresión Génica, Precondicionamiento Isquémico/métodos, Yeyuno/irrigación sanguínea, Yeyuno/patología, Arteria Mesentérica Superior, Isquemia Mesentérica/genética, Isquemia Mesentérica/patología, Distribución Aleatoria, Ratas Wistar, Reacción en Cadena en Tiempo Real de la Polimerasa, Valores de Referencia, Daño por Reperfusión/prevención & control, Reproducibilidad de los Resultados

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Ischemic postconditioning assessment in the liver of rats undergoing mesenteric ischemia and reperfusion

Abstract Introduction: Ischemic postconditioning is a method that shows evidence of efficacy in minimizing reperfusion injury; however, its effectiveness in preventing injuries in distant organs is still unknown, especially in those who have undergone mesenteric ischemia and reperfusion. Objective: To ...