Propofol attenuates cytokine-mediated upregulation of expression of inducible nitric oxide synthase and apoptosis during regeneration post-partial hepatectomy
Acta cir. bras; 32 (5), 2017
Abstract Purpose: To determine the effects of propofol and ketamine anesthesia on liver regeneration in rats after partial hepatectomy (PHT). Methods: Male Wistar albino rats were assigned randomly to four groups of 10. Anesthesia was induced and maintained with propofol in groups 1 and 2, and with ket...
Anestésicos Intravenosos/farmacología, Apoptosis, Ketamina/farmacología, Regeneración Hepática/efectos de los fármacos, Óxido Nítrico Sintasa de Tipo II/metabolismo, Propofol/farmacología, Anestésicos Intravenosos/metabolismo, Factor Apoptótico 1 Activador de Proteasas/metabolismo, Hepatectomía, Interleucina-6/sangre, Interleucina-6/metabolismo, Ketamina/metabolismo, Modelos Animales, Óxido Nítrico Sintasa de Tipo III/metabolismo, Antígeno Nuclear de Célula en Proliferación/metabolismo, Propofol/metabolismo, Distribución Aleatoria, Ratas Wistar, Regulación hacia Arriba