SUMMARY: Resveratrol (RES) and quercetine (QRC), is a promising agent relevant for both cancer chemoprevention and treatment via several signaling pathways, involved in their anticancer activity related to its chemotherapeutic potential, associated with the induction of ROS generation in cancer cells, le...
T
agetes patula
, known as French Marigold, belongs to the family Asteraceae. Human
papillomavirus infection is considered one of the causes of cervical cancer. This study assessed
the
cytotoxic activity and intracellular oxidative capacity of compounds isolated from e...
Cancer cells
modify lipid metabolism to proliferate,
Passiflora edulis
(
P. edulis
) fruit juice
(ZuFru) has antitumor activity, but whether a mechanism is through modulation of cell lipids is unknown.
T
o establish if ZuFru modifies cholesterol and triglycerides in SW480
and SW620...
Passiflora/química,
Extractos Vegetales/administración & dosificación,
Anticarcinógenos,
Jugos de Frutas y Vegetales/análisis,
Neoplasias Colorrectales/tratamiento farmacológico,
Proliferación Celular/efectos de los fármacos,
Colesterol,
Triglicéridos,
Línea Celular Tumoral/efectos de los fármacos,
Extractos Vegetales/química,
Fenoles/análisis,
Flavonoides/análisis,
Antioxidantes,
Supervivencia Celular/efectos de los fármacos,
Polisacáridos/análisis
Triterpenes are very important secondary metabolites with wide structural diversity and
significant role in pharmacy and medicine.
In the present research, a comparative study of
pharamacological activities of the triterpene fractions obtained from several pla...
SUMMARY: Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is highly expressed in various types of cancers including breast cancer. However, the role of AhR with its endogenous ligand 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) on the progression...
Indoles/administración & dosificación,
Tiazoles/administración & dosificación,
Receptores de Hidrocarburo de Aril/efectos de los fármacos,
Neoplasias de la Mama/patología,
Indoles/farmacología,
Tiazoles/farmacología,
Receptores de Estrógenos,
Inmunohistoquímica,
Proliferación Celular/efectos de los fármacos,
Citometría de Flujo,
Ensayos de Migración Celular,
Western Blotting,
Línea Celular Tumoral/efectos de los fármacos,
Citocromo P-450 CYP1A1/genética,
Citocromo P-450 CYP1B1/genética
Clausena excavata is a famous folklore medicinal plant in Asian region that is being used for the treatment of different disorders. This study investigated the cytotoxic effects of leaf extracts via MTT assay, as well as the in vitro apoptotic activities of the ethyl acetate C. excavata leaf extract (E...
Linfoma de Burkitt/tratamiento farmacológico,
Clausena/química,
Apoptosis/efectos de los fármacos,
Línea Celular Tumoral/efectos de los fármacos,
Extractos Vegetales/uso terapéutico,
Plantas Medicinales,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Acetatos,
Supervivencia Celular/efectos de los fármacos,
Reacción en Cadena de la Polimerasa,
Expresión Génica,
Anexina A5,
Proteína X Asociada a bcl-2,
Apoptosis/genética,
Fitoquímicos/análisis,
Concentración 50 Inhibidora,
Fluoresceína-5-Isotiocianato
Grewia tenax (Forssk.) Fiori (Malvaceae) grows in the Arabian Peninsula and is used for several medicinal purposes. To characterize the dermatological bioactivities of G. tenax in terms of its antimelanoma, antityrosinase and antioxidant activities. Cytotoxicity was assesse...
Grewia/química,
Melanoma/tratamiento farmacológico,
Antioxidantes/farmacología,
Neoplasias Cutáneas/tratamiento farmacológico,
Arabia Saudita,
Técnicas In Vitro,
Extractos Vegetales/farmacología,
Línea Celular Tumoral/efectos de los fármacos,
Monofenol Monooxigenasa/antagonistas & inhibidores,
Hojas de la Planta,
Especies Reactivas de Oxígeno,
Lupanos/análisis,
Sitoesteroles/análisis,
Antioxidantes/química,
Extractos Vegetales/química,
Cromatografía Líquida de Alta Presión
Pavón, Alequis;
Corsini, Gino;
Orellana, Paz;
Calisto, Nancy;
Navarro, Laura;
Wiese, Guillermo;
Cortés-Cortés, Piedad;
Gidekel, Manuel;
Gutierrez-Moraga, Ana;
Salazar, Lorena.
SUMMARY: Cancer is the second leading cause of death in the world and colorectal cancer is the only cancer that has shown a sustained increase in mortality in the last decade. In the search for new chemotherapeutic agents against cancer, extremophilic microorganisms have shown to be a potential source to...
Microbiología del Suelo,
Regiones Antárticas,
Bacillus/fisiología,
Bacillus/aislamiento & purificación,
Bacillus/genética,
Proliferación Celular/efectos de los fármacos,
Neoplasias Colorrectales/tratamiento farmacológico,
Línea Celular Tumoral/efectos de los fármacos,
Supervivencia Celular/efectos de los fármacos,
ARN Ribosómico 16S,
Fenotipo,
Genotipo,
Técnicas In Vitro,
Adenocarcinoma/tratamiento farmacológico,
Reacción en Cadena de la Polimerasa
Plants are a source of multiple antineoplastic treatments. However, the effect of many species used in traditional medicine has yet to be demonstrated. In this work, the taxonomic identification of Agave mapisaga was made and a high-performance liquid chromatography-mass spectromet...
This study reports the biotechnological importance of seven Lippia albaspecimens collected in different places in Brazil, and evaluation of some activities as larvicidal against Aedes spp., antifungal against dermatophytes; cytotoxicity against SNB-19 (astrocytoma), HCT-116 (human col...
Lippia/química,
Aceites Volátiles/química,
Antineoplásicos/química,
Plantas Medicinales,
Brasil,
Control Biológico de Vectores,
Terpenos/análisis,
Biotecnología,
Larvicidas,
Antifúngicos,
Inhibidores de la Colinesterasa,
Antineoplásicos/farmacología,
Aceites Volátiles/farmacología,
Línea Celular Tumoral/efectos de los fármacos,
Aedes/efectos de los fármacos
